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Now showing items 11-20 of 53
Elevated natural killer cell activity despite altered functional and phenotypic profile in Ugandans with HIV-1 Clade A or Clade D infection.
(Lippincott Williams & Wilkins, 2009)
Background and Objective: Natural killer (NK) cells most likely contribute toward limiting HIV-1 replication, and investigation into their function throughout the course of infection is therefore important. We here aimed ...
Oesophageal cancer management guidelines for Uganda.
(Association of Surgeons of East Africa and College of Surgeons of East Central and Southern Africa, 2009)
In Uganda, Oesophageal cancer is the third commonest malignancy in men and the fourth commonest in women, with an age standardized incidence rate of 13 - 14 per 100,000 of the population1,2. It remains a challenging tumour ...
Improving the quality of interpersonal communication skills of clinical officers at Moi Teaching and Referral Hospital, Eldoret, Kenya
(2009-08-08)
The way health care providers communicate has been linked to proximate outcomes such as patient satisfaction and recall, and to final outcomes, such as client compliance with treatment regimes and improved health results ...
Severe sepsis in two Ugandan hospitals: a prospective observational study of management and outcomes in a predominantly HIV-1 infected population
(Public Library of Science, 2009-11-11)
Background: Sepsis likely contributes to the high burden of infectious disease morbidity and mortality in low income countries. Data regarding sepsis management in sub-Saharan Africa are limited. We conducted a prospective ...
A novle polymorphism in ABCB1 gene, CYP2B6*6 and sex predict single dose efavirenz population pharmacokinetics in Ugandans
(Wiley-Blackwell, 2009)
AIMS Efavirenz exhibits pharmacokinetic variability causing varied clinical response. The aim was to develop an integrated population pharmacokinetic/pharmacogenetic model and investigate the impact of genetic variations, ...
Strategies to optimize HIV treatment outcomes in resource-limited settings
(Permanyer Publications, 2009)
Although the availability of antiretroviral therapy has increased rapidly to reach over three million people in low- and middle-income countries, coverage remains low as only 31% of people in need were receiving antiretroviral ...
The effect of AIDS defining conditions on immunological recovery among patients initiating antiretroviral therapy at Joint Clinical Research Centre, Uganda
(BioMed Central, 2009-07-24)
Background: Many HIV-infected patients only access health care once they have developed advanced symptomatic disease resulting from AIDS Defining Conditions (ADCs). We carried out a study to establish the effect of ADCs ...
Improving the quality of interpersonal communication skills of clinical officers at Moi Teaching and Referral Hospital, Eldoret, Kenya
(2009-08-08)
The way health care providers communicate has been linked to proximate outcomes such as patient satisfaction and recall, and to final outcomes, such as client compliance with treatment regimes and improved health results ...
The costs and effectiveness of four HIV counseling and testing strategies in Uganda
(Lippincott, Williams & Wilkins, 2009)
Objective: HIV counseling and testing (HCT) is a key intervention for HIV/AIDS control, and new strategies have been developed for expanding coverage in developing countries. We compared costs and outcomes of four HCT ...
Theoretical basis for reducing time-lines to the determination of positive Mycobacterium tuberculosis cultures using thymidylate kinase (TMK) assays
(BioMed Central, 2009-03-18)
Background: In vitro culture of pathogens on growth media forms a "pillar" for both infectious disease diagnosis and drug sensitivity profiling. Conventional cultures of Mycobacterium tuberculosis (M.tb) on Lowenstein ...