• Hepatitis B and C seroprevalence among health care workers in a tertiary hospital in Rwanda 

  Kateera, Fredrick; Walker, Timothy D.; Mutesa, Leon; Mutabazi, Vincent; Musabeyesu, Emmanuel; Mukabatsinda, Constance; Bihizimana, Pascal; Kyamanywa, Patrick; Karenzi, Ben; Orikiiriza, Judy T. (Oxford University Press, 2015)

  Background: Hepatitis B (HBV) and hepatitis C (HCV) are significant global public health challenges with health care workers (HCWs) at especially high risk of exposure in resource-poor settings. We aimed to measure HBV and ...

• Estimation of mortality among HIV-infected people on antiretroviral therapy treatment in East Africa: a sampling based approach in an observational, multisite, cohort study 

  Geng, Elvin H.; Odeny, Thomas A.; Lyamuya, Rita E.; Nakiwogga Muwanga, Alice; Diero, Lameck; Bwana, Mwebesa; Muyindike, Winnie; Braitstein, Paula; Somi, Geoffrey R.; Kambugu, Andrew; Bukusi, Elizabeth A.; Wenger, Megan; Wools-Kaloustian, Kara K.; Glidden, David V.; Yiannoutsos, Constantin T.; Martin, Jeffrey (Elsevier, 2015)

  Background—Mortality after initiation of antiretroviral treatment (ART) among HIV-infected patients in resource limited settings is a critical measure of the effectiveness and comparative effectiveness of the global public ...

• Modelling factors associated with covid-19 mortality among patients admitted to Dr. Sumait Hospital in Mogadishu Somalia : implementing parametric AFT models 

  Mohamed, Ali Hashi (Makerere University, 2025)

  Background: The coronavirus disease of 2019 (COVID-19) is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The first case of COVID-19 in Somalia was confirmed on March 16, 2020. The World Health ...

• Multiple validated measures of adherence indicate high levels of adherence to generic HIV antiretroviral therapy in a resource-limited setting 

  Oyugi, Jessica H.; Byakika-Tusiime, Jayne; Charlebois, Edwin D.; Kityo, Cissy; Mugerwa, Roy; Mugyenyi, Peter; Bangsberg, David R. (Lippincott Williams & Wilkins, 2004)

  Background: There are no validated measures of adherence to HIV antiretroviral therapy in resource-poor settings. Such measures are essential to understand the unique barriers to adherence as access to HIV antiretroviral ...

• Growing older with HIV in the treat-all era 

  Rajasuriar, Reena; Cran, HeidiM; Semeere, Aggrey S. (Wiley, 2022)

  One of the most impactful global public health interventions of modern times has been antiretroviral therapy (ART). This has led to reduced HIV transmission; reduced morbidity from opportunistic infections; and dramatically ...

• Implementing screening for hypertension in archetypal HIV primary care: a mixed-methods assessment 

  Buzaalirwa, Lydia; Nambala, Lydia; Banturaki, Grace; Lutung Amor, Penninah; Katahoire, Anne; Geng, Elvin; Semeere, Aggrey (BMC, 2022)

  Background: High prevalence of HIV and hypertension in sub-Saharan Africa puts adults living with HIV (ALWH) at high risk of end-organ complications. Both World Health Organization (WHO) and national guidelines recommend ...

• Increased prevalence of pregnancy and comparative risk of program attrition among individuals starting HIV treatment in East Africa 

  Holmes, Charles B.; Yiannoutsos, Constantin T.; Elul, Batya; Bukusi, Elizabeth; Ssali, John; Kambugu, Andrew; Cohen, Craig; Williams, Carolyn; Diero, Lameck; Padian, Nancy; Wools-Kaloustian, Kara K.; Musick, Beverly S (PLoS ONE, 2018)

  Background The World Health Organization now recommends initiating all pregnant women on life-long antiretroviral therapy (ART), yet there is limited information about the characteristics and program outcomes of pregnant ...

• Midwives’ perceptions towards the Ministry of Health guidelines for the provision of immediate postpartum care in rural health facilities in Uganda 

  Namutebi, Mariam; Nalwadda, Gorrette K.; Kasasa, Simon; Muwanguzi, Patience A.; Kaye, Dan K. (BMC, 2023)

  Background Guidelines for clinical practice have been part of the Ministry of Health’s efforts to improve the quality of care for over two decades. Their benefits have been documented in Uganda. However, having practice ...

• Readiness of rural health facilities to provide immediate postpartum care in Uganda 

  Namutebi, Mariam; Nalwadda, Gorrette K.; Kasasa, Simon; Muwanguzi, Patience A.; Ndikuno, Cynthia Kuteesa; Kaye, Dan K. (BMC, 2023)

  Background Nearly 60% of maternal and 45% of newborn deaths occur within 24 h after delivery. Immediate postpartum monitoring could avert death from preventable causes including postpartum hemorrhage, and eclampsia among ...

• Cryptococcal disease in the era of “test and treat”: Is there cause for concern? 

   Abassi, Mahsa;  Rhein, Joshua;  Meya, David B.;  Boulware, David R. (Oxford University Press, 2017)

  Treatment of cryptococcosis requires deferred initiation of antiretroviral therapy (ART). Early ART initiation may be detrimental in the context of cryptococcal infection by increasing the risk of immune reconstitution ...

• Delayed sputum culture conversion in tuberculosis human immunodeficiency virus–coinfected patients with low isoniazid and rifampicin concentrations 

  Sekaggya-Wiltshire, Christine ; Braun, Amrei von; Lamorde, Mohammed ;  Ledergerber, Bruno; Buzibye, Allan ; Henning, Lars ; Musaazi, Joseph ; Gutteck, Ursula ;  Denti, Paolo;  de Kock, Miné; Jetter, Alexander ; Byakika-Kibwika, Pauline ; Eberhard, Nadia ; Matovu, Joshua ; Joloba, Moses ;  Muller, Daniel; Manabe, Yukari C. ; Kamya, Moses R. ; Corti, Natascia ;  Kambugu, Andrew;  Castelnuovo, Barbara;  Fehr, Jan S. (Oxford Academic, 2018)

  Background. The relationship between concentrations of antituberculosis drugs, sputum culture conversion, and treatment outcome remains unclear. We sought to determine the association between antituberculosis drug ...

• Cellular immune activation in cerebrospinal fluid from Ugandans with cryptococcal meningitis and immune reconstitution inflammatory syndrome 

  Meya, David B.; Okurut, Samuel; Zziwa, Godfrey; Rolfes, Melissa A.; Kelsey, Melander; Cose, Steve; Joloba, Moses; Naluyima, Prossy; Palmer, Brent E.; Kambugu, Andrew; Mayanja-Kizza, Harriet; Bohjanen, Paul R.; Eller, Michael A.; Wahl, Sharon M.; Boulware, David R.; Manabe, Yuka C.; Janoff, Edward N. (Oxford University Press, 2015)

  Background. Human immunodeficiency virus (HIV)-associated cryptococcal meningitis (CM) is characterized by high fungal burden and limited leukocyte trafficking to cerebrospinal fluid (CSF). The immunopathogenesis of CMimmune ...

• Correlation between co-therapy of efavirenz-based ART and pregnancy among HIV-positive women on hormonal contraceptive implants at TASO Tororo-Uganda: A retrospective review 

  Okoboi, Stephen; Eunice, Ajambo; Oceng, Ronald; Etukoit, Bernard (2018)

  Background: We examined the association between EFV and non-EFV based ART regimens and pregnancy outcomes among women who were on HCI in a peri-urban HIV clinic in Tororo, Uganda. Methods: We reviewed and extracted routinely ...

• Effects of HIV infection and ART on phenotype and function of circulating monocytes, natural killer, and innate lymphoid cells 

  Nabatanzi, Rose; Cose, Stephen; Joloba, Moses; Rowland Jones, Sarah; Nakanjako, Damalie (BioMed Central, 2018)

  HIV infection causes upregulation of markers of inflammation, immune activation and apoptosis of host adaptive, and innate immune cells particularly monocytes, natural killer (NK) and innate lymphoid cells (ILCs). Although ...

• Prevalence of lipodystrophy and metabolic abnormalities in HIV-infected African children after 3 years on first-line antiretroviral therapy 

  Bwakura-Dangarembizi, Mutsawashe; Musiime, Victor; Szubert, Alexander J.; Prendergast, Andrew J.; Gomo, Zvenyika A.; Thomason, Margaret J.; Musarurwa, Cuthbert; Mugyenyi, Peter; Nahirya, Patricia; Kekitiinwa, Adeodata; Gibb, Diana M.; Walker, Ann S.; Nathoo, Kusum (Lippincott, 2015)

  Background: Most pediatric lipodystrophy data come from high-income/ middle-income countries, but most HIV-infected children live in sub-Saharan Africa, where lipodystrophy studies have predominantly investigated stavudine-based ...

• Impaired renal function and associated risk factors in newly diagnosed HIV-infected adults in Gulu Hospital, Northern Uganda 

  Odongo, Pancras; Wanyama, Ronald; Obol, James Henry; Apiyo, Paska; Byakika-Kibwika, Pauline (BioMed Central, 2015)

  Background: Screening for renal diseases should be performed at the time of diagnosis of human immunodeficiency virus (HIV) infection. Despite the high prevalence of HIV/AIDS in Northern Uganda, little is known about the ...

• Feasibility of conducting a pilot randomized control trial of a psycho-education intervention in patients with a first episode psychosis in Uganda—A study protocol 

  Akena, Dickens; Semeere, Aggrey; Kadama, Philippa; Mwesiga, Emmanuel K.; Nakku, Juliet; Nakasujja, Noeline (PLoS ONE, 2022)

  Background. Psychotic disorders contribute to significant morbidity and mortality partly due to the chronicity of the illness and high relapse rates. Delivering psycho-education messages about disease etiology, their signs ...

• Gastrointestinal cryptococcoma – Immune reconstitution inflammatory syndrome or cryptococcal relapse in a patient with AIDS? 

  Musubire, Abdu K.; Meya, David B.; Lukande, Robert; Kambugu, Andrew; Bohjanen, Paul R.; Boulware, David R. (Elsevier, 2015)

  The introduction of antiretroviral therapy (ART) may lead to unusual paradoxical and unmasking presentations of opportunistic infections. Intra-abdominal cryptococcosis is a rare manifestation of Cryptococcus. We present ...

• Predictors and outcomes of mycobacteremia among HIV-infected smear- negative presumptive tuberculosis patients in Uganda 

  Nakiyingi, Lydia; Ssengooba, Willy; Nakanjako, Damalie; Armstrong, Derek; Holshouser, Molly; Kirenga, Bruce J.; Shah, Maunank; Mayanja-Kizza, Harriet; Joloba, Moses L.; Ellner, Jerrold J.; Dorman, Susan E.; Manabe, Yukari C. (BioMed Central Infectious Diseases, 2015)

  Background: Sputum smear microscopy for tuberculosis (TB) diagnosis lacks sensitivity in HIV-infected symptomatic patients and increases the likelihood that mycobacterial infections particularly disseminated TB will be ...

• Evaluation of four chemotherapy regimens for treatment of advanced AIDS-associated Kaposi Sarcoma in Kenya: A cost-effectiveness analysis 

  Freeman, Esther E.; McCann, Nicole C.; Semeere, Aggrey; Reddy, Krishna P.; Laker-Oketta, Miriam; Byakwaga, Helen; Pei, Pamela P.; Fernandez, Maya E Hajny; Kiprono, Samson; Busakhala, Naftali; Martin, Jeffery N; Maurer, Toby; Bassett, Ingrid V.; Freedberg, Kenneth A.; Hyle, Emily P. (Elsevier, 2022)

  Background The most effective treatment for advanced AIDS-associated Kaposi sarcoma is paclitaxel or pegylated liposomal doxorubicin (PLD); neither is routinely used in sub-Saharan Africa due to limited availability and ...

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