College of Health Sciences (CHS)
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Incidence and immediate outcomes of in-hospital cardiac arrest in Healthcare institutions on the Mulago hill
(Makerere University, 2024-10-28)Background: In-hospital cardiac arrest (IHCA) is an acute event that can occur to any hospitalized patient. It is associated with high morbidity and mortality and constitutes a significant healthcare burden worldwide. ... -
Stress, Associated factors and coping strategies among undergraduate medical students at Makerere university medical school: A cross sectional study
(Makerere University, 2021)Overview: Stress refers to how the body reacts and adjusts to any changes in the physical, mental and physiological environment (Melaku et al., 2015). The medical course has been proven to be one of the most stressful by ... -
Performance evaluation of truenat test for detection of pulmonary tuberculosis among HIV symptomatic patients at Lira Regional Referral Hospital
(Makerere University, 2024)Background: About a quarter of the world’s population has been infected with Mycobacterium tuberculosis, in immune compromised people like in HIV- infected persons, the risk of developing tuberculosis is 22 times higher. ... -
Delayed definitive treatment among trauma patients attending oral and maxillofacial surgery unit of Mulago Hospital, Uganda : prevalence and associated factors
(Makerere University, 2023)Oral and maxillofacial (OMF) trauma or injuries are common presentations in hospital emergency rooms and account for about 50% of all deaths globally. The definitions of delayed definitive treatment of OMF injuries vary ... -
HIV-1 drug resistance among adults on integrase inhibitors with virologic failure at Medical Research Council, Uganda: Prevalence, associated factors and diagnostic accuracy of next generation sequencing
(Makerere University, 2024)Emerging evidence suggests a high rate of drug resistance (DR) associated with integrase strand transfer inhibitors (INSTIs) in developed countries, though there is limited information on DR during INSTI treatment in Uganda. ... -
Effect of substitution mutations on the temporal dynamics of HIV-1 subtype A1 and D in the Ugandan epidemic
(Makerere University, 2024)Background: Subtypes A1, D and inter-subtype recombinants dominate the Uganda HIV-1 epidemic. This diversity has affected disease diagnosis and therapeutics. Predictive modeling could guide better understanding of the ... -
Identification of unique molecular signatures in the envelope Glycoproteins of HIV-1 transmitted/founder viruses from East Africa
(Makerere University, 2024)Background: HIV-1 mucosal transmission undergoes a genetic bottleneck that allows a single virus termed HIV-1 Transmitted/Founder (T/F) virus to establish a productive clinical infection in most heterosexual transmission ... -
Effect of milk protein and whey permeate in large quantity lipid-based nutrient supplement on growth and early child development among children with stunting in Uganda
(Makerere University, 2023)Background: Stunting affects 22% of children under 5 years globally, putting them at risk of adverse outcomes including delayed development. Nearly half of the children in low- and middle-income country settings (LMICs) ... -
Characterization of ESBL producing gram negative uropathogenic bacteria isolated from patients with urinary yract infections from Mbeya, Tanzania
(Makerere University, 2024)Background: The emergence and spread of drug-resistant pathogens, such as ESBL-producing Gram-negative bacteria continue to threaten our ability to treat common infections causing a huge burden to our healthcare systems. ... -
Development of an antigen capture ELISA for detection of SARS-CoV-2
(Makerere University, 2024)Background. In December 2019, the World Health Organization (WHO) declared COVID-19 a global pandemic causing over 700 million cases and more than 7 million deaths globally. In Uganda, over 40,408 cases with 334 deaths ... -
Methicillin resistant staphylococcus on inanimate objects in paediatric treatment units of Mulago National Referral Hospital
(Makerere University, 2024)Background: Hospital environment and inanimate surfaces have been reported to be colonised by different pathogens. Contact with colonised objects may lead to pathogen transmission resulting in increased morbidity and ... -
Prevalence and factors associated with hemorrhoids among adult patients attending colorectal clinic at Mulago National Referral Hospital: A cross-sectional study
(Makerere University, 2014)BACKGROUND: Hemorrhoidal disease is one of the most common benign anorectal conditions. The estimated prevalence of hemorrhoids has been reported in western literature to range from 4.4% to as high as 88% depending on the ... -
Birth preparedness and complications' readiness among mothers attending the antenatal care clinic at Katakwi General Hospital, Eastern Uganda
(Makerere University, 2024)Introduction: Birth preparedness and complications readiness is an essential component of the antenatal care that is intended to reduce delays by the pregnant mothers to access skilled care for birth and related complications. ... -
Replication, fine-mapping and causal inference of genetic loci associated with major depressive disorder among participants of the Uganda genome resource.
(Makerere University, 2024-10-17)Background: Major depressive disorder (MDD) is the leading cause of disability worldwide, with significant consequences like poor health outcomes, premature death, and reduced productivity. Twin-based studies have shown ... -
T cell immune memory and protective correlates in Ugandans with mild Covid-19 disease.
(Makerere University, 2024-10-22)Background: This study explores T cell immune memory and protective correlates in Ugandans with mild COVID-19 disease, focusing on those with low immunoglobulin G (IgG) antibody levels. Understanding the mechanisms that ... -
Predicting suicidality in people living with HIV in Uganda: A machine learning approach
(Makerere University, 2024-10)Background Suicidality is a major risk factor for future suicide attempts and completed suicide. People living with HIV (PLWH) are at a higher risk of fatal suicide attempts compared to the general population due to the ... -
Impact of blended learning on the academic performance of pharmacology students of Victoria University, Kampala: Quasi experimental study
(Makerere University, 2024)Introduction: - As technology advances, innovative teaching-learning practices are advancing in higher education globally. The 21st century skills require stakeholders of higher education to be acquainted with the emerging ... -
Extended spectrum beta lactamase gram negative bacteria contamination of inanimate objects in Paediatric wards at Mulago National Referral Hospital in Uganda
(2024)Background: Antimicrobial resistance (AMR) is a global crisis that endangers the efficacy of antibiotics and also the treatment provided. Extended Spectrum Beta Lactamase (ESBL) resistance among beta lactams especially ... -
Malaria prevalence and associated factors among pregnant women attending their first antenatal care in Nakivale Refugee Settlement
(Makerere University, 2024)Background: Malaria is the leading cause of morbidity and mortality in Uganda affecting mostly children under 5 years of age and pregnant mothers. In the post COVID-19 era, malaria incidences have been reportedly rising ... -
Functional and radiological outcomes of closed ankle fractures managed non-operatively among adults at Mulago National Referral Hospital six months post-injury
(Makerere University, 2024)Introduction Non-operative management is a common approach for treating closed ankle fractures at Mulago National Referral Hospital (MNRH) due to its potential benefits, including shorter hospital stays and the absence ...