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Now showing items 61-70 of 73
The influence of pre-hospital treatment of fever on severity of malaria among children 6-59 months presenting at Mulago Hospital: A case-control study.
(Makerere University, 2014)
Introduction: Delivery of prompt and adequate treatment for malaria at the community level remains a strategy to reduce the burden of malaria in sub-Saharan Africa. As a result of this many patients with suspected malaria ...
Factors influencing utilization of paediatric HIV care and treatment services in Njombe Region, Tanzania
(Makerere University, 2014)
Introduction and Background: HIV/AIDS is one of the major cause of child death in Tanzania (UNICEF, 2012). However, utilization of HIV care and treatment services is very low in this setting (NACP, 2013). This study therefore ...
Outcomes and predictors of survival among children with hodgkin lymphoma at Uganda Cancer Institute
(Makerere University, 2022-11)
Background: Hodgkin Lymphoma (HL) is one of the most curable childhood malignancies. HL represents 6% of all childhood cancers and has an incidence rate of 12 cases/million/year in the 0–14-year age group worldwide It has ...
Exploring the global genetic diversity of P. falciparum Pf113 malaria vaccine candidate gene
(Makerere University, 2022)
The malaria disease burden is still of great concern especially in sub-Saharan Africa among children below the age of 5 years. Evolution of the P. falciparum parasite in response to intervention measures as well as the ...
Pharmacokinetic/pharmacodynamic Modeling to optimize efavirenz dosing in HIV/AIDs infected children from Sub-Saharan Africa.
(Makerere University, 2022-12)
Aim:Using a model‐based approach, the efavirenz steady‐state pharmacokinetics in Sub-Saharan African children is characterized, quantifying demographic and genotypic effects on the drug's disposition. Simulations are also ...
Transfusion Challenges in Patients with Hematological Malignancies in Sub-Saharan Africa: A Prospective Observational Study from the Uganda Cancer Institute
(Makerere University, 2020)
Blood transfusion is fundamental in managing hematologic malignancies. We sought to evaluate the need and availability of blood products for patients with hematological malignancies at Uganda Cancer Institute. We prospectively ...
Revalence and factors associated with hyperuricaemia among diabetes mellitus patients at Kiruddu National Referral Hospital, Uganda
(Makerere University, 2022-08)
Background: The prevalence of hyperuricemia is increasing around the world, especially among patients with diabetes mellitus (DM). Hyperuricemia leads to worsening hyperglycemia, and this accelerates the progression of ...
Association between indoor residual spraying and pregnancy outcomes: a quasi-experimental study from Uganda
(Oxford University Press, 2022)
Background: Malaria is a risk factor for adverse pregnancy outcomes. Indoor residual spraying with insecticide (IRS) reduces malaria infections, yet the effects of IRS on pregnancy outcomes are not well established. We ...
Rhomboids of mycobacteria: insight from phylogeny, genomic and complementation analysis.
(Makerere University, 2014)
Background
The rhomboid superfamily of proteins includes novel trans-membrane Serine-proteases that occur in all life-kingdoms, and are responsible for vital roles such as signaling in Drosophila, red blood cell invasion ...
An assessment of implementation science research capacity in Uganda
(BioMed Central, 2021)
Background: In Uganda and other resource-poor countries, relevant research findings face a tortuous path to translation into policy and routine practice. Implementation science (ImSc) research could facilitate faster ...