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Short report: assessing the impact of indoor residual spraying on malaria morbidity using a sentinel site surveillance system in Western Uganda
(American Society of Tropical Medicine and Hygiene, 2009)
A single round of indoor residual spraying (IRS) using lambda-cyhalothrin was implemented in a district of Uganda with moderate transmission intensity in 2007. Individual patient data were collected from one health facility ...
Factors associated with development of severe malaria in children under 5 years in Kanungu District
(Makerere University, 2004)
Malaria remains a major public health problem in Uganda. In Kanungu District, malaria is responsible for 40% of all outpatient visits, 25% admissions and 14% in-patient deaths. Ninety percent of these deaths are among ...
Update on the efficacy, effectiveness and safety of artemether–lumefantrine combination therapy for treatment of uncomplicated malaria
(Dove Medical Press, 2009)
Artemether–lumefantrine is one of the artemisisnin-based combination therapies recommended for treatment of uncomplicated falciparum malaria. The drug combination is highly efficacious against sensitive and multidrug ...
Treatment of severe sepsis with Artemether-Lumefantrine Is associated with decreased mortality in Ugandan patients without malaria
(American Society of Tropical Medicine and Hygiene, 2009)
We enrolled 382 patients at two hospitals in Uganda in a prospective observational study of severe sepsis. Because artemisinins improve survival in murine sepsis models, we performed a post hoc analysis of the association ...
Laboratory medicine in Africa: a barrier to effective health care
(University of Chicago Press, 2006)
Providing health care in sub-Saharan Africa is a complex problem. Recent reports call for more resources to assist in the prevention and treatment of infectious diseases that affect this population, but policy makers, ...
Delayed care seeking for fatal pnemonia in children aged under five years in Uganda: a case-series study
(World Health Organization, 2008)
Objective To review individual case histories of children who had died of pneumonia in rural Uganda and to investigate why these children did not survive. Methods This case-series study was done in the Iganga/Mayuge ...
Artemether-lumefantrine versus dihydroartemisinin-piperaquine for treatment of malaria: a randomized trial.
(2007-05-18)
Objectives: To compare the efficacy and safety of artemether-lumefantrine (AL) and dihydroartemisinin-piperaquine (DP) for treating uncomplicated falciparum malaria in Uganda. Design: Randomized single-blinded clinical ...
Some aspects of malaria in Mulago Hospital
(1974)
Thirty patients with malaria were studied. Seven had cerebral malaria, ten severe and thirteen non-severe malaria. Age ranged from seven weeks to eight years with equal sex distribution. All were febrile except two infants ...
Artesunate plus mefloquine versus mefloquine for treating uncomplicated malaria (Review)
(Cochrane Collaboration, 2010)
Background
Multiple-drug-resistant malaria is widespread, and in South-East Asia resistance is high against nearly all single therapy antimalarial drugs. Here, and in other areas with low malaria transmission, the combination ...
Genetic polymorphisms in plasmodium falciparum associated with resistance to artemisnin combination therapy: complexity of infection during short-term culture and characterization of in-vitro sensitivity in Kampala Uganda
(2010)
Background Artemisinin-based combination therapy (ACT) is currently advocated in Africa as a means of improving treatment efficacy and slowing the development of drug resistance. However, the selection of resistant parasites, ...