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Now showing items 11-20 of 22
Practices of diagnosis and treatment of pulmonary tuberculosis, associated factors, barriers and facilitators among private practitioners in Kampala, Uganda
(Makerere University, 2020-11)
Introduction: Globally, tuberculosis (TB) is a leading cause of morbidity and mortality accounting for an estimated 10.0 million new cases and 1.451million deaths in 2018. Uganda is one of the world’s high TB burden countries ...
Test and treat policy: Effect on ART initiation and retention and health system barriers and facilitators to implementation in AHF Uganda Cares Clinics in Central Uganda
(Makerere University, 2022-05)
Background: The ‘Test and Treat’ policy was introduced by the WHO in 2015 as a measure to extend the benefits of ART to all HIV positive patients and, in a bid to enable the achievement of the UNAIDS 95-95-95 2030 ...
Prevalence, immunological profile, and factors associated with latent tuberculosis infection among adults with diabetes mellitus at Kiruddu National Referral Hospital
(Makerere University, 2022-10)
Introduction: The dual epidemic of Diabetes Mellitus (DM) and tuberculosis (TB) is a growing public health challenge in Sub-Saharan Africa (SSA), Uganda inclusive. Due to the immunologic dysfunction associated with diabetes ...
Prevalence of chronic obstructive pulmonary disease and associated factors among HIV infected patients attending the Mulago ISS Clinic
(Makerere University, 2017-10-12)
Background: Chronic obstructive pulmonary disease (COPD) will be the 3rd leading cause of death worldwide by 2020. Data from Africa indicate that the prevalence of COPD is high (4% to 25%). We sought to determine its ...
Prevalence and factors associated with depressive illness in patients with tuberculosis in Mulago Hospital
Background: Depression is a major cause of the global disease burden and globally affects 350-400 million persons making it the largest contributor to years lived with disability. Among patients with chronic physical ...
Prevalence and factors associated with pulmonary tuberculosis among children aged 2 to 59 months presenting with severe pneumonia at Alsabah Children’s Hospital, Juba, South Sudan
(Makerere University, 2019-09)
Background: Tuberculosis (TB) is a major public health problem at a global level. According to the World Health Organization (WHO) in 2018, approximately 10 million people developed TB in 2017, of which 1.0 million (10%) ...
Strain diversity of mycobacterium tuberculosis non-Uganda isolates from patients with pulmonary tuberculosis in Kawempe
(Makerere University, 2013-05)
Background: Tuberculosis is a major public health problem in peri-urban areas of Kampala and Uganda in general. To date there is inconclusive information about strain diversity of Mycobacterium tuberculosis of the non ...
Effect of vitamin d binding protein gene polymorphisms and vitamin d bioavailability on cathelicidin expression in tuberculosis infection and disease
(Makerere University, 2023-01)
Background: The human antimicrobial peptide cathelicidin (LL-37) is involved in host innate immunity by the after activation of Toll-like receptors (TLRs), resulting in direct killing of Mycobacterium tuberculosis (MTB). ...
Effect of COVID-19 period on tuberculosis treatment success; A mixed methods study among tuberculosis patients at Jinja Regional Referral Hospital
(Makerere University, 2022-01)
Introduction: Before the COVID-19 pandemic, over 4000 people were dying from TB every day. TB is still a major public health threat globally, but the TB epidemic may be exacerbated by the COVID-19 pandemic. The lockdown ...
Performance evaluation of the Uganda National Algorithm for Diagnosis of tuberculosis in children at Mulago National Referral Hospital-Kampala, Uganda
(Makerere University, 2023)
Background
Diagnosing childhood tuberculosis (TB) is a challenge, this led the Uganda national tuberculosis control program (NTLP) to develop a clinical treatment decision algorithm for children. However, there is limited ...