dc.contributor.author | Worodria, W | |
dc.contributor.author | Okot-Nwang, M | |
dc.contributor.author | Yoo, S. D. | |
dc.contributor.author | Aisu, Thomas | |
dc.date.accessioned | 2012-09-25T09:43:05Z | |
dc.date.available | 2012-09-25T09:43:05Z | |
dc.date.issued | 2003 | |
dc.identifier.citation | Worodria, W., Okot-Nwang, M., Yoo, S. D. & Aisu, T. (2003). Causes of lower respiratory infection in HIV-infected Ugandan adults who are sputum AFB smear-negative. The International Journal of Tuberculosis and Lung Disease, 7(2):117–123. | en_US |
dc.identifier.issn | 1027-3719 | |
dc.identifier.uri | http://hdl.handle.net/10570/679 | |
dc.description.abstract | SETTING: Mulago national referral and teaching hospital.
OBJECTIVE: To assess the etiology of lower respiratory infections in HIV-infected Ugandan adults who are sputum acid-fast bacilli (AFB) smear-negative.
DESIGN: A descriptive cross-sectional study. Participants included consecutive adult patients admitted to medical wards with respiratory symptoms of at least 3 weeks and infiltrates on chest radiograph. Those who were sputum AFB smear-negative and HIV-positive underwent bronchoscopy and bronchoalveolar lavage (BAL). BAL fluid was obtained and stained for AFB and Pneumocystis carinii, and cultured for bacteria and fungi.
RESULTS: Of 198 patients screened, 48 were sputum smear-positive for AFB. Sixty-seven were excluded for various reasons, leaving 83 patients who met the inclusion criteria and underwent bronchoscopy: 32 (38.6%) patients had P. carinii infection, 20 (24%) had pulmonary tuberculosis, nine (11%) had pulmonary Kaposi’s
sarcoma and pyogenic bacteria were identified in seven (8%). No aetiological diagnosis was found in 24 (30%) patients.
CONCLUSION: P. carinii and Mycobacterium tuberculosis were the commonest causes of disease among sputum AFB smear-negative, HIV-positive adults presenting
to Mulago Hospital. Pulmonary Kaposi’s sarcoma and pyogenic bacteria occurred with less frequency. | en_US |
dc.description.sponsorship | Uganda TB and Leprosy Control Programme
(UNTLP) and Sexually Transmitted Infections Project (STIP) | en_US |
dc.language.iso | en | en_US |
dc.publisher | IUATLD | en_US |
dc.subject | Smear-negative PTB | en_US |
dc.subject | Pneumocystis carinii | en_US |
dc.title | Causes of lower respiratory infection in HIV-infected Ugandan adults who are sputum AFB smear-negative | en_US |
dc.type | Journal article, peer reviewed | en_US |