Browsing School of Bio-Medical Sciences (Bio-Medical) by Issue Date "2010"

Now showing items 1-10 of 10

    • Comparison of methods in the recovery of nucleic acids from archival formalin-fixed paraffin-embedded autopsy tissues 

      Okello, John B. A.; Zurek, Jaymi; Devault, Alison M.; Kuch, Melanie; Okwi, Andrew L.; Sewankambo, Nelson K.; Bimenya, Gabriel S.; Poinar, Debi; Poinar, Hendrik N. (Elsevier, 2010)
      Archival formalin-fixed paraffin-embedded (FFPE) human tissue collections are typically in poor states of storage across the developing world. With advances in biomolecular techniques, these extraordinary and virtually ...

    • Genetic variations in ABCB1 and CYP3A5 as well as sex influence quinine disposition among Ugandans 

      Mukonzo, Jackson K; Waako, Paul; Ogwal-Okeng, Jasper; Gustafsson, Lars L.; Aklillu, Eleni (Lippincott Wilkins & Williams, 2010)
      Abstract: Quinine is one of the most effective antimalarial drugs, although its clinical use is limited as a result of its narrow safety margin. Quinine is a substrate of the polymorphic p-glycoprotein and CYP3A4/3A5. This ...

    • In silico prediction of efavirenz and rifampicin drug–drug interaction considering weight and CYP2B6 phenotype 

      Rekic´, Dinko; Röshammar, Daniel; Mukonzo, Jackson K; Ashton, Michael (The British Pharmacological Society, 2010)
      AIMS This study aimed to test whether a pharmacokinetic simulation model could extrapolate nonclinical drug data to predict human efavirenz exposure after single and continuous dosing as well as the effects of concomitant ...

    • Levels of Bifurcation of the Sciatic Nerve among Ugandans at School of Biomedical Sciences Makerere and Mulago Hospital Uganda 

      Kukiriza, J.; Kiryowa, H.; Turyabahika, J.; Ochieng, J.; Ibingira, C.B.R. (East and Central African Journal of Surgery, 2010)
      Background: The sciatic nerve is derived from the lumbo-sacral plexus, It is the thickest nerve in the whole body, it exits the gluteal region through the lower part of the greater sciatic foramen, it is the main innervator ...

    • NeuroAIDS in Africa 

      Robertson, Kevin; Liner, Jeff; Hakim, James; Sankalé, Jean-Louis; Grant, Igor; Letendre, Scott; Clifford, David; Diop, Amadou Gallo; Jaye, Assan; Kanmogne, Georgette; Njamnshi, Alfred; Langford, T. Dianne; Weyessa, Tufa Gemechu; Wood, Charles; Banda, Mwanza; Hosseinipour, Mina; Sacktor, Nad; Nakasuja, Noeline; Bangirana, Paul; Paul, Robert; Joska, John; Wong, Joseph; Boivin, Michael; Holding, Penny; Kammerer, Betsy; Van Rie, Annelies; Ive, Prudence; Nath, Avindra; Lawler, Kathy; Adebamowo, Clement; Royal III, Walter; Joseph, Jeymohan (Informa Healthcare, 2010)
      In July 2009, the Center for Mental Health Research on AIDS at the National Institute of Mental Health organized and supported the meeting “NeuroAIDS in Africa.” This meeting was held in Cape Town, South Africa, and ...

    • Plasma levels of DDT/DDE and liver function in malaria control personnel prior to DDT in-door residual spray in Northern Uganda, 2008 

      Bimenya, G. S.; Okwi, A. L.; Olwa, F.; Habalurema, M.; Okot, J. P.; Lugemwa, M. (African Journal of Animal and Biomedical Sciences, 2010)
      Where 20 million Ugandans are debilitated by malaria in a year, there is continued need of dichlorodiphenyltrichloroethane (DDT) for vector control while further research is implemented to clarify the health impact of ...

    • Proceedings of the Uganda Medical Laboratory Technology Association (UMLTA) 

      Uganda Medical Laboratory Technology Association; Federation of East African Association of Medical Laboratory Scientists (Uganda Medical Laboratory Technology Association (UMLTA), 2010)
      THE 28TH UMLTA & 5th FEAMLS SCIENTIFIC CONFERENCE THEME: “STRENGTHENING MEDICAL LABORATORY DELIVERY SYSTEM, -A GATEWAY TO ACHIEVING MILLENIUM DEVELOPMENT GOALS” Date: 18th - 19th November 2010 Venue: Churchill Courts Hotel - Gulu

    • Quantitative assessment of the sensitivity of various commercial reverse transcriptases based on armored HIV RNA 

      Okello, John B. A.; Rodriguez, Linda; Poinar, Debi; Bos, Kirsten; Okwi, Andrew L.; Bimenya, Gabriel S.; Sewankambo, Nelson K.; Henry, Keneth R.; Kuch, Melanie; Poinar, Hendrik N. (Public Library of Science, 2010)
      Background: The in-vitro reverse transcription of RNA to its complementary DNA, catalyzed by the enzyme reverse transcriptase, is the most fundamental step in the quantitative RNA detection in genomic studies. As such, ...

    • The reliability of sickling and solubility tests and peripheral blood film method for sickle cell disease screening at dictrict health centers in Uganda 

      Okwi, A. L.; Parkes, A.; Ocaido, M.; Byarugaba, W. (Clinics in Mother and Child Health, 2010)
      Although sickling and solubility tests and peripheral blood film methods are today available for sickle cell disease screening in Uganda, their reliability and ease of applicability have not been determined. This study was ...

    • An up-date on the prevalence of sickle cell trait in Eastern and Western Uganda. 

      Okwi, A.L.; Byarugaba, Wilson; Ndugwa, Christopher M.; Parkes, Arthur; Ocaido, Michael; Tumwine, James K. (BioMed Central, 2010)
      Background: The first survey on sickle cell disease (SCD) done in Uganda in 1949, reported the district of Bundibugyo in Western Uganda to have the highest sickle cell trait (SCT) prevalence (45%). This is believed to be ...