Browsing School of Bio-Medical Sciences (Bio-Medical) by Type
Now showing items 21-40 of 224
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Bacille calmette-guérin, diphtheria-tetanus, and measles vaccine responses of infants born to mothers with active tuberculosis disease
(Makerere University, 2023-11-14)Background: Babies born to mothers with active tuberculosis disease (ATB) are at risk of poor clinical outcomes such as low birth weight and perinatal mortality. However, little is known about the influence of maternal ... -
Bacterial profile and antimicrobial susceptibility patterns of isolates from surgical site infections at Luwero hospital
(Makerere University, 2023-11-14)Background: A surgical site infection (SSI) is an infection that develops within at most 30 days following a surgical procedure or after one year in case if an implant was placed. The American Centers for Disease Control ... -
Bacterial-Derived Outer Membrane Vesicles in Chronic Obstructive Pulmonary Disease and HIV Infection in a Ugandan Population
(Makerere University, 2023-11-01)Background: The prevalence of chronic obstructive pulmonary disease (COPD) has increased among people living with HIV (PLWH) despite the global scale-up of antiretroviral therapy (ART). Currently, it is not fully known ... -
Bacteriological quality analysis of herbal cosmetics sold in Kampala District, Uganda
(Makerere University, 2011-07)The use of herbal cosmetics is popular in Uganda. Despite the increase in consumer trust for these products, the bacteriological quality of herbal cosmetics sold in Kampala has remained unknown. Regulatory polices on herbal ... -
Barriers to partner HIV serostatus disclosure among postnatal mothers on option b+ in Rukungiri district
(Makerere University, 2019-12-02)Introduction; Self-disclosure of one’s positive HIV serostatus to partners is an important step in the pathway of transmission prevention through sexual risk reduction and uptake of treatment and support services. Disclosure ... -
BCL-2 protein expression in oral squamous cell carcinoma and associated clinicopathological features as seen at the Pathology Department, Makerere University
(Makerere University, 2021-11)Background: Predicting clinical behavior of oral squamous cell carcinoma based on histopathological analysis requires immunohistochemical supplementation with biomarkers like Bcl-2 protein that can be used in prognostic ... -
Binding characteristics of selected commercial antibodies against recombinant HIV Subtype D P24 antigens
(Makerere University, 2023-01)The standard method for monitoring HIV treatment response is quantitative RT-PCR, but it is difficult to implement in low and middle income countries due to infrastructure and personnel requirements. Point of care technologies ... -
BRCA1 and BRCA2 mutations in selected exons in breast cancer patients attending Mulago Hospital, Uganda
(Makerere University, 2017-02)Breast cancer 1 (BRCA1) and Breast cancer 2 (BRCA2), mutation recognition is crucial for cancer risk assessment, identification of suitable breast cancer treatments, and personalised breast cancer prophylaxis in mutation ... -
Breast Cancer Molecular Subtype Prevalence and Commonly Mutated Genes in Triple Negative Breast Cancer in Uganda
(Makerere University, 2022-11-25)Breast cancer is the second commonest cancer in women in Uganda, accounting for about 21% of all cancer related mortality in women in Uganda. An estimated 35-36% of all breast cancer patients in Uganda have triple negative ... -
Carbapenemase producing Enterobacterieceae carriage among health care workers in selected units of Mulago national referral hospital and Uganda heart institiute
(Makerere University, 2018-10)Background:Antimicrobial resistance is a global public health concern contributing to increased morbidity and mortality particularly in low income countries where infection control is often inadequate. Multidrug-resistant ... -
The challenge posed by lay catechists’ poverty to their effectiveness in evangelization in the light of redemptoris missio in Kasanga Parish, Kasese Catholic Diocese
(Makerere University, 2015-04)It is true the Bishop is primarily the agent of Evangelization; this becomes very vivid when he has a very good team of coworkers, like the priests, Nuns, religious brothers and Catechists. Right back from the early ... -
Characterisation of Candida africana among pregnant women with vaginitis
(Makerere University, 2023-11)Candida africana, an emerging variant within the Candida albicans complex, has a global intra-albicans complex prevalence of 1.67% and varies between 0% and 8.4% depending on the region. It mainly causes vulvovaginal ... -
Characterisation of pelvic types, inlet and outlet views using computed tomography in the Ugandan population
(Makerere University, 2022-07)Introduction Radiographic assessment of the pelvis requires AP, inlet and outlet views. The pelvic inlet and outlet views have traditionally been done at 45o cranially and caudally respectively. While these views have ... -
Characterisation of Resistance Associated Variants (RAVs) to the newly approved anti-tuberculosis drugs Delamanid, Pretomanid, Bedaquiline, Clofazimine and Linezolid in isolates from a 2016/2017 Tanzanian Anti-Tuberculosis Drug Resistance Survey
(Makerere University, 2022)Background: Drug-resistant Tuberculosis (TB) undermines the effort to curb TB disease. It is associated with higher treatment costs, longer treatment periods and more adverse effects (Jeon, 2015). Recently, three new ... -
Characterization of extended spectrum βlactamases elaborated in enterobacteriaceae in Uganda.
(Makerere University, 2017-08-23)Background: Extended spectrum β-lactamase producing Enterobacteriaceae (ESBL-PE) have been identified as a major cause of both community and facility associated infections and are closely linked to faecal carriage in the ... -
Characterization of performance of three commercial monoclonal antibodies in detection of spike protein in SARS-CoV-2
(Makerere University, 2024)The study aimed at characterizing the Performance of three commercial monoclonal antibodies in detection of spike protein in SARS-CoV-2. This was looking at avidity and specificity of the monoclonal antibodies which would ... -
Characterizing microbial diversity and resistome in urban sewage using shotgun metagenomics in Kampala, Uganda
(Makerere University, 2023-05)Introduction: Recently, antimicrobial resistant (AMR) infections have shown up as the leading threat to human health, having 700,000 directly attributed estimated deaths per year worldwide. For Africa, AMR data is still ... -
Characterizing the composition of the airway microbiota of patients with COPD in a rural setting in Uganda using shotgun metagenomics, a case control study
(Makerere university, 2022-10-25)Introduction: Diverse airway microbiota play an important role in the development and integrity of the immune system that limits growth of pathogenic microorganisms and clearing bacterial infections. Community shifts from ... -
Colistin resistance among gram negative rods carried in the intestinal tract of patients admitted in the ICU of Mulago National Referral Hospital
(Makerere University, 2022-04)Background: The limited options for treatment of infections caused by MDR or XDR bacteria prompted the reintroduction of colistin, which coupled with extensive use in food-producing animals is driving increasing resistance ... -
Combined antiretroviral treatment modification among HIV infected patients in New Nyanza Provincial General Hospital, Western Kenya
(2012-06)Background Limited combined antiretroviral therapy (cART) regimens in resource constrained settings call for the need to optimize the available options in order to improve the durability of potent and well-tolerated first ...