Browsing School of Medicine (Sch. of Med.) by Subject "Malaria"
Now showing items 1-20 of 30
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Adherence to malaria management guidelines by health care workers in the Busoga Sub-region, Eastern Uganda
(BMC, 2022)Background: Appropriate malaria management is a key malaria control strategy. The objective of this study was to determine health care worker adherence levels to malaria case management guidelines in the Busoga sub-region, ... -
The age-specific incidence of hospitalized paediatric malaria in Uganda
(BMC, 2020)Background: Understanding the relationship between malaria infection risk and disease outcomes represents a fundamental component of morbidity and mortality burden estimations. Contemporary data on severe malaria risks ... -
Association between indoor residual spraying and pregnancy outcomes: a quasi-experimental study from Uganda
(Oxford University Press, 2022)Background: Malaria is a risk factor for adverse pregnancy outcomes. Indoor residual spraying with insecticide (IRS) reduces malaria infections, yet the effects of IRS on pregnancy outcomes are not well established. We ... -
Associations between aminoquinoline resistance genotypes and clinical presentations of Pplasmodium falciparum Infection in Uganda
(American Society for Microbiology., 2020)Mutations that mediate resistance of Plasmodium falciparum to aminoquinoline antimalarials are selected by prior drug use and may alter parasite fitness, but associations with clinical presentations are uncertain. We ... -
Cognition, behaviour and academic skills after cognitive rehabilitation in Ugandan children surviving severe malaria: a randomised trial
(BioMed Central, 2011)Background: Infection with severe malaria in African children is associated with not only a high mortality but also a high risk of cognitive deficits. There is evidence that interventions done a few years after the illness ... -
A cost effectiveness analysis of quinine or artemisinins in management of severe malaria in pregnancies at Mulago Hospital.
(Makerere University, 2014)Introduction: Malaria kills one million people each year in the world. It accounts for up to 40% of all outpatient attendances, 20% of all admissions and 14% of all in-patient deaths in Uganda. Among pregnant women, it ... -
Effect of HIV-Infection on parasite clearance in pregnant women with severe malaria in Lacor and Gulu hospitals, Northern Uganda.
(2009-05)TITTLE: Effect of HIV infection on parasite clearance in pregnant women with severe malaria in Lacor and Gulu hospitals, Northern Uganda. INTRODUCTION: Malaria and HIV/AIDS share determinants of vulnerability and have ... -
Evaluating Initiatives to support evidence-informed health system policy-making in Cameroon and Uganda: Case studies of EVIPNet Cameroon and REACH-PI Uganda
(Makerere University, 2022-11)Background: During the last twenty years, fostering evidence informed health system policymaking (EIHSP) in low- and middle- income countries (LMICs) has been a priority for national and global health players with the aim ... -
Genetic polymorphisms in plasmodium falciparum associated with resistance to artemisinin combination therapy: complexity of infection during short-term culture and characterization of in vitro sensitivity in Kampala Uganda
(Makerere University, 2010)Background: Artemisinin-based combination therapy (ACT) is currently advocated in Africa as a means of improving treatment efficacy and slowing the development of drug resistance. However, the selection of resistant ... -
Immunity to malaria
(1970)Section I: literature is reviewed and the pattern of the development of immunity in a population exposed to high malarial endemicity is followed. This is followed by a brief discussion of specific aspects of malarial ... -
Impact of the second and third COVID-19 waves on out patient malaria indicators and case management guidelines at selected sites with varying malaria transmission intensities in Uganda.
(Makerere University, 2023-01-20)Background: COVID-19 has imposed negative impacts on the fight against malaria in many malaria endemic countries. We aimed to assess the impact of the second and third COVID-19 waves on outpatient malaria indicators and ... -
The Influence of pre-hospital treatment of fever on severity of malaria among children 6-59 months presenting at Mulago Hospital: A case-control study
(Makerere University, 2014)Introduction: Delivery of prompt and adequate treatment for malaria at the community level remains a strategy to reduce the burden of malaria in sub-Saharan Africa. As a result of this many patients with suspected malaria ... -
Iron status in patients with plasmodium falciparum malaria and anaemia in Mulago hospital
(2002)Malaria is an important cause of morbidity and mortality in Uganda. It is associated with a wide range of complications including severe anaemia especially in children. Anaemia impairs motor and cognitive development in ... -
Malaria case management and associated factors for children under-five years at Abim and Kaabong General Hospitals in Karamoja Sub-Region, Uganda
(Makerere university, 2021-03)Introduction: Malaria still remains a global health concern, despite the availability of effective prevention and treatment measures. Inappropriate case management is one of the known risk factors for disease progression ... -
Malaria diagnosed in an urban setting strongly associated with recent overnight travel: A case–control study from Kampala, Uganda
(2020)Malaria is frequently diagnosed in urban Kampala, despite low transmission intensity. To evaluate the association between recent travel out of Kampala and malaria, we conducted a matched case–control study. Cases were ... -
Malaria hospitalisation in East Africa: age, phenotype and transmission intensity
(BMC, 2022)Background: Understanding the age patterns of disease is necessary to target interventions to maximize cost-effective impact. New malaria chemoprevention and vaccine initiatives target young children attending routine ... -
Malaria treatment practice and clinical presentation of adult patients with antimalarial prescriptions in Mulago hospital assessment centre.
(Makerere University, 2013)Back ground: Malaria is a major cause of morbidity and mortality worldwide. It is endemic in over 95% of Uganda and accounts for 25-40% of all outpatient attendances. The World Health Organisation recommends parasitological ... -
Malaria with neurological involvement in Ugandan children: effect on cognitive ability, academic achievement and behaviour
(BioMed Central, 2011-11-03)Background Malaria is a leading cause of ill health and neuro-disability in children in sub-Saharan Africa. Impaired cognition is a common outcome of malaria with neurological involvement. There is also a possibility ... -
Practical implications of a relationship between health management information system and community cohort–based malaria incidence rates
(2020)Global malaria burden is reducing with effective control interventions, and surveillance is vital to maintain progress. Health management information system (HMIS) data provide a powerful surveillance tool; however, its ... -
Presumptive treatment with sulphadoxine-pyrimethamine versus weekly chloroquine for malaria prophylaxis in children with sickle cell anaemia in Uganda: a randomized controlled trial
(BioMed Central, 2009-10-24)Background: Malaria carries high case fatality among children with sickle cell anaemia. In Uganda, chloroquine is used for prophylaxis in these children despite unacceptably high levels of resistance. Intermittent presumptive ...