Browsing School of Medicine (Sch. of Med.) by Subject "Antiretroviral therapy"
Now showing items 1-20 of 26
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Antiretroviral therapy improves cognitive impairment in HIV individuals in Sub-Saharan Africa
(American Academy of Neurology (AAN), 2006)Abstract—Background: Highly active antiretroviral therapy (HAART) can improve cognitive performance in some patients with HIV-associated cognitive impairment in the United States. The effect of HAART on HIV dementia ... -
Cardiac dysfunction among HIV infected children on combination antiretroviral therapy attending joint clinical research centre, Kampala, Uganda.
(Makerere University, 2013)Introduction Human Immunodeficiency virus still remains a global problem. Cardiac dysfunction is highly prevalent among symptomatic ART naïve HIV infected children with advanced disease. Earlier studies have described ... -
Clinical, immunological, virological characteristics, and hospitalisation outcomes of patients admitted to Kiruddu Hospital with advanced HIV disease
(Makerere University, 2022-08)Introduction Nearly four decades after the first case of AIDS was described, the global number of AIDS related deaths is not declining as expected to meet elimination targets, especially in sub-Saharan Africa where the ... -
Cognitive dysfunction among HIV positive and HIV negative patients with psychosis in Uganda
(Public Library of Science, 2012)Background: Cognitive impairment is an established phenomenon in HIV infected individuals and patients that have psychosis. However there is need to establish the severity of the impairment if patients are co morbid with ... -
Dissertation barriers to timely initiation of antiretroviral therapy among HIV infected children admitted to mulago hospital paediatric wards.
(2007-08)BACKGROUND: The median survival of HIV infected children in the absence of treatment is 2 years, thus early initiation of ART is desirable. In Uganda, ART is now being provided free of charge. However, some children still ... -
The effect of Aids defining conditions on immunological recovery among patients initiating antiretroviral therapy at JCRC, Kampala, Uganda
(2008-10)BACKGROUND: During 2005, the world health organization (WHO) estimated that there were over 1.3 million people receiving antiretroviral therapy (ART). As the number of individuals able to access treatment is ever increasing, ... -
Hepatitis B in Uganda: Transmission and prevention strategies among infants and HIV-infected adults
(Makerere University, 2022-10)This thesis is focused on hepatitis B virus (HBV) transmission and prevention in the setting of human immune deficiency syndrome (HIV) infection. HBV is common among HIV-infected persons in part due to shared modes of ... -
HIV viral load suppression and associated factors among people with mental disorders at Butabika Hospital and Mulago ISS Clinics: A mixed methods study
(Makerere University, 2022-12)INTRODUCTION In 2017 Uganda adopted the universal test and treat (UTT) guidelines. According to the UTT guidelines, people who test positive for HIV should be immediately initiated on antiretroviral therapy (ART) regardless ... -
Human immunodeficiency virus neurological complications: An overview of the Ugandan experience.
(Journal of NeuroVirology, 2005)Sub-Saharan Africa, which has about 12% of the global population, is home to almost 70% of individuals infected with human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS). A recent survey by the ... -
In vivo PPD reactivity and associated factors among HIV positive patients on HAART at the Makerere University Infectious Diseases Clinic.
(2009-08)BACKGROUND: It is estimated that a third of the world’s population is infected with tuberculosis (TB). This epidemic is fueled by HIV, with reactivation rates of 8-10% / year and overall lifetime risk of 30% in HIV ... -
Incidence and predictors of mortality and the effect of tuberculosis immune reconstitution inflammatory syndrome in a cohort of TB/HIV patients commencing antiretroviral therapy
(Lippincott Wilkins & Williams, 2011)Background: Tuberculosis-HIV (TB-HIV) coinfection remains an important cause of mortality in antiretroviral therapy (ART) programs. In a cohort of TB-HIV–coinfected patients starting ART, we examined the incidence and ... -
Longitudinal patients’ cohorts for impactful research and HIV care at the Infectious Diseases Institute
(2022)Introduction Observational studies provide important evidence supporting the feasibility and effectiveness of health interventions. The 20-year-old Infectious Diseases Institute (IDI) established to respond to infectious ... -
Low-level viraemia: An emerging concern among people living with HIV in Uganda and across sub-Saharan Africa
(AOSIS, 2022)Attaining viral load (VL) suppression for over 95% of the people living with HIV on antiretroviral therapy is a fundamental step in enabling Uganda and other sub-Saharan African countries to achieve global Sustainable ... -
Mobile Phone-based intervention to promote un-interrupted HIV treatment during the COVID-19 pandemic
(2022)Introduction: Keeping HIV-infected adults away from the health care system during the COVID-19 travel restrictions, presents a challenge to HIV treatment adherence. Methods: This study focused on the initial two phases ... -
Predictors for delayed initiation of antiretroviral therapy in HIV-infected patients admitted in Mulago Hospital
(Makerere University, 2013-05)Background: Over half of medical admissions at Mulago Hospital present with advanced HIV disease and have not yet initiated antiretroviral therapy (ART). There is increasing evidence from AIDS clinical trials and cohorts ... -
Predictors of unknown HIV serostatus at the time of labor and delivery in Kampala, Uganda.
(Elsevier Ireland, 2013)Objective: To determine factors associated with an unknown HIV serostatus among pregnantwomen admitted in labor to Mulago Hospital, Kampala, Uganda. Methods: In total, 665 pregnant women admitted to Mulago Hospital were ... -
Prevalence and associated factors of HIV positive status disclosure to family members and the lived experiences by women attending Kalisizo General Hospital ART Clinic
(Makerere University, 2020)Background: HIV is still an epidemic infection globally with 38 million infected with it. HIV positive status disclosure is an important factor in HIV/AIDS prevention interventions and plays a role in ART adherence. However, ... -
Prevalence and factors associated with dyslipidemia among adult patients on dolutegravir based antiretroviral regimen at Mengo Hospital, A cross-sectional study
(Makerere University, 2022-12)Introduction: Dolutegravir (DTG) based anti-retroviral therapy (ART) regimen has been rolled out in Uganda as the preferred first- and second-line treatment option in the management of Human Immunodeficiency Virus (HIV). ... -
Prevalence and factors associated with non-adherence to HAART among HIV-Positive women in reproductive age in Kayunga District
(2009-05)Introduction: Globally approximately 40.3million people are infected with HIV, of which more 25.8million are in sub-Sahara Africa in 2007. Women living in sub-Saharan Africa are more affected by HIV/AIDS than any other ... -
Prevalence and factors associated with postpartum Haemorrhage among Human Immunodeficiency Virus infected women delivered at Kawempe National Referral Hospital
(Makerere University, 2024)Background PPH is the leading cause of maternal mortality in Uganda and globally. In Uganda some studies have investigated HIV infection as a risk factor for PPH but very few of these studies have been conducted in ...