College of Health Sciences (CHS): Recent submissions
Now showing items 1-20 of 3310
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Prevalence, correlates, and predictive value of high-risk human papillomavirus mRNA detection in a community-based cervical cancer screening program in Western Uganda
(BMC, 2019)Background: New strategies are needed to combat the high incidence of cervical cancer in resource-limited settings such as sub-Saharan Africa. Screening for high-risk human papillomavirus (hrHPV) DNA is sensitive for ... -
Longer-term effectiveness of protease-inhibitor-based second line antiretroviral therapy in four large sub-Saharan African clinics
(Elsevier, 2019)Objectives: Data on the longer-term effectiveness of second line combination antiretroviral therapy (ART) in sub-Saharan Africa (SSA) are lacking. We sought to assess the probability and determinants of 2nd line ART ... -
Severity of post - operative knee stiffness and associated factors after surgical fixation of knee osseous injuries among adults at Mulago National Referral Hospital
(Makerere University, 2025-05)Background: Knee stiffness following surgical fixation of knee osseous injuries is a common and potential complication of surgery and rehabilitation with a global incidence of 4% to 38%. Even with the currently recommended ... -
The 14-day incidence and risk factors of gastrointestinal anastomotic leak among adult patients in Mulago Hospital, a prospective cohort study
(Makerere University, 2025)Background: Anastomotic leak is one of the most feared complications following gastrointestinal (GI) anastomotic surgery. It increases morbidity and mortality of patients undergoing GI surgery. Globally, the frequency of ... -
Prevalence and factors associated with hypertension among female nurses in private healthcare facilities in Jinja City
(Makerere University, 2024)Introduction: Hypertension affects 1.3 billion people globally and is predicted to rise to 1.56 billion by 2025, influenced by urbanization, sedentary lifestyles, and dietary shifts. Despite being essential to Uganda's ... -
Experiences of adult patients with cancer at a specialized cancer care facility in Uganda
(Wolters Kluwer Health Inc., 2025)Background: The experiences of adult cancer patients in low-income countries regarding health care and infrastructure are largely undocumented. This study aimed to describe the experiences of adult men and women receiving ... -
Adult patients with cancer in Uganda: validation of the tool, health-related quality of life, and patient experiences
(Makerere University, 2025)Background: This study aimed to assess the validity and reliability of the Luganda version of the tool used to measure health-related quality of life (HRQoL), specifically the European Organisation for Research and Treatment ... -
Prevalence and factors associated with pre-operative delays among neurotraumatic patients at Mulago National Referral Hospital: a cross-sectional study
(Makerere University, 2025)Introduction Neurotraumatic emergencies affect more than 10 million people globally with majority of them from sub-Saharan. Neurotraumatic emergencies present a challenge in emergency surgical care, demanding quick and ... -
An assessment of organisational knowledge management for health: a case study of a non-governmental organisation in Kampala, Uganda
(Makerere University, 2023)Knowledge management is a discipline that promotes an integrated approach to identifying, capturing, evaluating, retrieving, and sharing information assets. Knowledge management involves people, processes, and technology ... -
Prevalence and grading of meconium-stained amniotic fluid plus associated puerperal sepsis within 7 days at Kawempe National Referral Hospital.
(Makerere University, 2024)Background: Meconium-stained amniotic liquor remains both a maternal and neonatal health challenge globally as it is associated with higher rate of caesarean delivery, increased need for neonatal resuscitation, puerperal ... -
Short term outcomes of unstable pelvic fractures in adults treated at Mulago National Referral Hospital
(Makerere University, 2025)Introduction Pelvic fractures are perhaps the most severe & life-threatening musculoskeletal injuries, constituting about 1.5%–3% of all skeletal injuries. Despite their severity, unstable pelvic fractures can yield ... -
Adult patients with cancer in Uganda : validation of the tool, health-related quality of life, and patient experiences
(Makerere University, 2025)Background: This study aimed to assess the validity and reliability of the Luganda version of the tool used to measure health-related quality of life (HRQoL), specifically the European Organization for Research and Treatment ... -
Depressive and anxiety symptoms predict sustained quality of life deficits in HIV-positive Ugandan adults despite antiretroviral therapy
(Lippincott, 2016)The impact of psychosocial status at onset of antiretroviral therapy on changes in quality of life (QOL) and subjectively rated health (SRH) among adults on ART in resource-limited settings is poorly understood. Therefore, ... -
Improving the Sensitivity of the Xpert MTB/RIF Assay on sputum pellets by decreasing the amount of added sample reagent: a laboratory and clinical evaluation
(American Society for Microbiology, 2015)The Xpert MTB/RIF(Xpert) assay permits rapid near-patient detection of Mycobacterium tuberculosis in sputum; however, the test sensitivity remains suboptimal in paucibacillary specimens that are negative for acid-fast ... -
Treatment of HIV/AIDS. Do the dilemmas only increase?
(American Medical Association, 2004)Physicians and other health care professionals who treat patients with human immunodeficiency virus (HIV)/AIDS are confronted daily with complex challenges. Fortunately, several articles in this theme issue of JAMA on ... -
Hepatitis B and C seroprevalence among health care workers in a tertiary hospital in Rwanda
(Oxford University Press, 2015)Background: Hepatitis B (HBV) and hepatitis C (HCV) are significant global public health challenges with health care workers (HCWs) at especially high risk of exposure in resource-poor settings. We aimed to measure HBV and ... -
Estimation of mortality among HIV-infected people on antiretroviral therapy treatment in East Africa: a sampling based approach in an observational, multisite, cohort study
(Elsevier, 2015)Background—Mortality after initiation of antiretroviral treatment (ART) among HIV-infected patients in resource limited settings is a critical measure of the effectiveness and comparative effectiveness of the global public ... -
Modelling factors associated with covid-19 mortality among patients admitted to Dr. Sumait Hospital in Mogadishu Somalia : implementing parametric AFT models
(Makerere University, 2025)Background: The coronavirus disease of 2019 (COVID-19) is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The first case of COVID-19 in Somalia was confirmed on March 16, 2020. The World Health ... -
Multiple validated measures of adherence indicate high levels of adherence to generic HIV antiretroviral therapy in a resource-limited setting
(Lippincott Williams & Wilkins, 2004)Background: There are no validated measures of adherence to HIV antiretroviral therapy in resource-poor settings. Such measures are essential to understand the unique barriers to adherence as access to HIV antiretroviral ... -
Growing older with HIV in the treat-all era
(Wiley, 2022)One of the most impactful global public health interventions of modern times has been antiretroviral therapy (ART). This has led to reduced HIV transmission; reduced morbidity from opportunistic infections; and dramatically ...