College of Health Sciences (CHS): Recent submissions
Now showing items 1-20 of 2973
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Carbapenem resistance among gram negative rods isolated from surgical site infections at Mulago and Kawempe National referral hospitals
(Makerere University, 2024-01-04)Background: Surgical site infections are becoming increasingly difficult to manage with the rise of drug resistance among causative bacteria. Contributing to this, the use of foreign implants in certain surgeries pauses ... -
Birth preparedness and complication readiness among pregnant mothers with previous uterine scar attending Kawempe National Referral Hospital-Uganda
(Makerere University, 2024)Introduction: Birth preparedness and complication readiness (BPCR) is aimed at reducing maternal and neonatal mortality by mitigating the three delays of obtaining maternal and Neonatal care. Previous uterine scar increases ... -
Prevalence of Nasal Carriage of Methicillin Resistant Staphylococcus Aureus Among Patients, Health Care Workers and Patients’ Care Takers at Kabale Regional Referral Hospital, South Western Uganda
(Archives of Clinical and Medical Microbiology, 2023-10-24)Background Methicillin Resistant Staphylococcus aureus (MRSA) is a type of Gram-positive bacterium that is genetically different from other strains of Staphylococcus aureus by virtue its capability to overcome the actions ... -
Antimicrobial Resistance Patterns and Molecular Characterization of Klebsiella pneumoniae in Clinical Isolates at Mbarara Regional Referral Hospital
(Scientific Research Publishing, 2019)Background: Klebsiella pneumoniae is one of the most frequent opportunistic pathogens causing a range of infections and being resistant for beta-lactamases (ESBL) and Carbapenemases. Aim: The aim of the present study was ... -
Bacteriological profle, antibiotic susceptibility and factors associated with neonatal Septicaemia at Kilembe mines hospital, Kasese District Western Uganda
(BMC, 2021)Introduction: Neonatal septicaemia is one of the most common leading causes of neonatal morbidity and mortality in developing countries. It is estimated to afect more than 30 million people worldwide annually, potentially ... -
Assessment of biosafety and biorisk management practices among medical laboratory students in two institutions in Uganda
(Elsevier, 2022)Medical laboratory workers handle clinical specimens, which are a threat of exposure to infectious agents. Notably, medical laboratory science students report for internships with only theoretical knowledge of biosafety ... -
Status of pulmonary fungal pathogens among individuals with clinical features of pulmonary tuberculosis at Mbarara University Teaching Hospital in Southwestern Uganda
(Therapeutic advances in infectious disease, 2021)Background: Pulmonary mycoses are important diseases of the respiratory tract caused by pulmonary fungal pathogens. These pathogens are responsible for significant morbidity and mortality rates worldwide; however, less ... -
Prevalence and outcomes of gastrectomy at Mulago National Referral Hospital; A cross-sectional study
(Makerere University, 2024)Background: Gastrectomy is a surgical procedure performed for various conditions of the stomach and duodenum. Despite its widespread use, there needs to be more data reporting in-hospital outcomes associated with gastrectomy ... -
Prevalence and factors associated with underweight status among infants in Tororo District Uganda
(Makerere University, 2017)INTRODUCTION Underweight in infants increases the risk of mortality (WHO, 2010 ). Globally, 16% of children below five years are underweight of these 17% are in developing countries and 21% in Sub – Sahara Africa ... -
Effect of COVID-19 and related interventions on access to veterinary antimicrobials and clinical services for management of common poultry diseases by poultry farmers in Hoima District, Western Uganda
(Makerere University, 2024)Background The poultry industry is an important contributor to daily human protein requirements as meat and eggs consumed. Among the major animal source foods in Hoima district, those from poultry rank highest. Unfortunately, ... -
Prevalence and factors associated with chronic pulmonary aspergillosis among post tuberculosis lung disease patients at Makerere University Lung Institute
(Makerere University, 2024)Introduction: As of 2021, there were around 10.6 million incident cases of tuberculosis (TB) worldwide, listing it as the leading cause of infectious-related death worldwide. Despite receiving a microbiological cure, ... -
Retention in care, viral suppression and factors associated with viral non-suppression among refugee adolescents infected with HIV at Kyangwali Refugee Settlement in Kikuube District, Uganda
(Makerere University, 2023)Introduction: Compared to HIV positive non-refugee adolescents, refugee adolescents are generally less likely to receive antiretroviral therapy, and access to the drugs is often inconsistent (UNHCR, 2015). This study aimed ... -
Investigating Metabolic and Molecular Ecological Evolution of Opportunistic Pulmonary Fungal Coinfections: Protocol for a Laboratory-Based Cross-Sectional Study
(JMIR, 2023-12)Background: Fungal-bacterial cocolonization and coinfections pose an emerging challenge among patients suspected of having pulmonary tuberculosis (PTB); however, the underlying pathogenic mechanisms and microbiome ... -
Plasmodium falciparum genetic diversity and multiplicity of infection based on msp‑1, msp‑2, glurp and microsatellite genetic markers in Sub-Saharan Africa: a systematic review and meta-analysis
(BMC, 2024)Background In sub-Saharan Africa (SSA), Plasmodium falciparum causes most of the malaria cases. Despite its crucial roles in disease severity and drug resistance, comprehensive data on Plasmodium falciparum genetic ... -
A comparison of frequencies and function of myeloid derived suppressor cells (MDSCS) IN TB/HIV co-infected and HIV mono-infected individuals in Uganda
(Makerere University, 2023)Background Myeloid-derived suppressor cells (MDSC) encompass a subset of myeloid cells, which suppress both innate and adaptive immune functions. These cells negatively regulate the immune function either by arginine ... -
Sero-antigen prevalence of lymphatic filariasis and risk factors of podoconiosis in Busiriba Sub-county, Kamwenge District, Southwestern Uganda, August–September 2018
(BMC, 2024)Objective Given the neglected nature of filariasis, especially in Uganda where data are scarce, this cross-sectional study aimed to determine the sero-antigen prevalence of lymphatic filariasis and risk factors associated ... -
Incidence and etiology of catheter associated urinary tract infection among admitted patients at Kabale Regional Referral Hospital, South Western Uganda
(Scientific Research Publishing, 2019)Introduction: Catheter Associated Urinary Tract Infection is the most common hospital acquired infection worldwide. Urinary Tract Infections among catheterised patients are on rise regardless of antibiotic use and this is ... -
Clindamycin resistance among methicillin resistant staphylococcus aureus isolated from human and respective household swine in greater Kabale Region—South Western Uganda
(Scientific Research Publishing, 2019)Introduction: S. aureus is recognized as the common cause of nosocomial and community-acquired infections. Macrolide-Lincosamide-Streptogramin B (MLSB) is thought to be alternative therapies against MRSA infections. Clindamycin ... -
Functioning and control of phagocytosis
(IntechOpen, 2023)Phagocytosis is a very complex and versatile process that contributes to immunity through a series of events that is it’s sometimes referred to the Come and Eat me process. Due to the recognition ingestion and digestion ... -
Laboratory Diagnosis of Candidiasis
(IntechOpen, 2022-08)The burden of Candidiasis continues to increase and so does the Candida species. Although Candida species are closely similar phenotypically, they differ from each other in terms of epidemiology, genetic characteristics, ...