College of Health Sciences (CHS): Recent submissions
Now showing items 1-20 of 3276
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Evaluation of four chemotherapy regimens for treatment of advanced AIDS-associated Kaposi Sarcoma in Kenya: A cost-effectiveness analysis
(Elsevier, 2022)Background The most effective treatment for advanced AIDS-associated Kaposi sarcoma is paclitaxel or pegylated liposomal doxorubicin (PLD); neither is routinely used in sub-Saharan Africa due to limited availability and ... -
Midwives’ perspectives about using individualized care plans in the provision of immediate postpartum care in Uganda; an exploratory qualitative study
(BMC, 2023)Introduction Individualized care planning has been slowly integrated into practice in Uganda with minimal documentation of how the concept is applied in providing care. This study explored the perceptions of midwives about ... -
Telling the story of intersectional stigma in HIV-associated Kaposi’s sarcoma in Western Kenya: A convergent mixed-methods approach
(Wiley Online Library, 2022)Introduction: The experience of stigma can be multifaceted for people with HIV and cancer. Kaposi’s sarcoma (KS), one of the most common HIV-associated cancers in sub-Saharan Africa, often presents with visible skin lesions ... -
Barriers and facilitators to chemotherapy initiation and adherence for patients with HIV-associated Kaposi’s sarcoma in Kenya: A qualitative study
(BMC, 2022)Background: Kaposi sarcoma is one of the most prevalent HIV‑associated malignancies in sub‑Saharan Africa and is often diagnosed at advanced stage of disease. Only 50% of KS patients who qualify for chemotherapy receive ... -
Viral load status before switching to dolutegravir-containing antiretroviral therapy and associations with Human Immunodeficiency Virus treatment outcomes in Sub-Saharan Africa
(Oxford University Press, 2021)Background. Dolutegravir is being rolled out globally as part of preferred antiretroviral therapy (ART) regimens, including among treatment-experienced patients. The role of viral load (VL) testing before switching patients ... -
Understanding diagnostic delays for kaposi sarcoma in Kenya: A qualitative study
(2022)Background: Although HIV-associated Kaposi sarcoma (KS) is frequently diagnosed at an advanced stage in sub-Saharan Africa, reasons for diagnostic delays have not been well described. Methods: We enrolled patients >18 years ... -
Postpartum care in Uganda: facility readiness, midwives perspectives, individualized care planning and patient outcomes
(Makerere university, 2025)Background: Globally, a woman dies every two minutes due to pregnancy or childbirth. Two-thirds of maternal deaths occur in the postpartum period and in Sub-Saharan Africa due to preventable causes such as sepsis, postpartum ... -
Marginal men, respectable masculinity and access to HIV services through intimate relationships with female sex workers in Kampala, Uganda
(Elsevier, 2022)Masculinity influences men’s sexual risk-taking behaviour and affects uptake of HIV services. We draw on data from a year-long (2019) ethnographic study focusing on men in relationships with female sex workers (FSW) in ... -
Factors associated with Rabies vaccination uptake by Dog owners in Butaleja Town Council, Butaleja District
(Makerere University, 2025)Introduction: Rabies, a deadly zoonotic disease, remains a global threat, especially in Africa and Asia. Despite being preventable through dog vaccination, low uptake persists, posing public health and economic risks. ... -
Assessing the knowledge and practices of health workers on the management of Rift Valley Fever in Kabale District, South Western Uganda
(Makerere University, 2024)Background: Rift Valley fever (RVF) is a zoonotic viral hemorrhagic disease caused by the Rift Valley Fever virus (RVFV), predominantly affecting Africa and the Arabian Peninsula. Majority of the outbreaks in Uganda are ... -
Assessing the effectiveness of contact tracing for multi drug resistant tuberculosis in Uganda
(Makerere University, 2024)Introduction: Multidrug-resistant tuberculosis (MDR-TB) poses a big threat in to the management of Tuberculosis (TB) disease in many countries including Uganda. MDR - TB can be transmitted from one person to another through ... -
Safety, effectiveness and acceptability of misoprostol for treatment of incomplete mid trimester abortion in Uganda
(Makerere University, 2023-07)Eight percent of the maternal deaths in Uganda are abortion-related and yet women still have limited access to quality postabortion care. Task sharing is a proposed strategy to increase access to safe postabortion care and ... -
Mobility patterns of index tuberculosis cases and tuberculosis transmission niches in Kampala
(Makerere University, 2024)Introduction: TB control relies on minimizing transmission from infectious to susceptible individuals. In Uganda, Kampala faces significant TB challenges, with index cases playing a key role in disease spread. Understanding ... -
Factors associated with HIV virological non-suppression among HIV positive children aged o-14 years on antiretroviral treatment at Jinja Regional Referral Hospital: Retrospective Cohort Study
(Makerere University, 2024)Background: Virological suppression is critical to treatment success and reducing child morbidity and mortality. However, children continue to register low virological suppression of 41% in comparison to 70% suppression ... -
Knowledge, attitudes and perceptions towards the proposed National Health Insurance Scheme amongst commercial motorcycle riders in Kampala
(Makerere University, 2024)Background: Uganda is seeking to achieve universal health coverage for its citizens by putting into action a National Health Insurance Scheme (NHIS). Commercial motor cycle riders are the most vulnerable motorists in Uganda, ... -
Factors affecting clinicians’ reporting of adverse drug reactions in Makindye Division, Kampala
(Makerere University, 2015)Background: Adverse Drug Reactions (ADRs) contribute significantly to the global health burden with their prevalence estimated to be 6.5% globally .The hospital setting is the best opportunity for monitoring the trends and ... -
Prevalence and factors associated with overweight and obesity among children aged 8-12 years in private primary schools in Kampala City, Uganda
(Makerere University, 2024)Background: Childhood overweight and obesity is a significant public health issue in developing countries. There is a dearth of data on populations at increased risk to guide targeted interventions. This study aimed to ... -
Treatment outcomes of isoniazid mono-resistant mycobacterium tuberculosis patients in Uganda: a retrospective cross-sectional study from 2017 to 2022
(Makerere University, 2024-10)Globally, isoniazid-resistant, rifampicin-susceptible TB is estimated to occur in 13.1% (95% confidence interval [CI]: 9.9–16.9%) of new cases and 17.4% (95% CI: 0.5–54.0%) of previously treated cases. Current WHO guidelines ... -
Occurrence of quinolone resistance genes qep, QnrA, QnrB and QnrS in uropathogenic E. coli from female clinical samples at Makerere University College of Health Sciences
(Makerere University, 2022)Drug resistant Escherichia coli (E Coli) is the leading cause of community and hospital acquired urinary tract infections affecting approximate 150 million people each year worldwide. Uropathogenic Escherichia coli (UPEC) ... -
Prevalence and factors associated with nasal fractures among patients with head trauma at Mulago National Referral Hospital
(Makerere University, 2024)Introduction: Nasal fractures are the most common type of facial fractures contributing 40 - 58% of all facial fractures. Although very common, their assessment and management is rarely included in the routine care of ...