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Retention in HIV care among adolescents living with HIV at Naguru Hospital: Effect of COVID-19 restrictive measures and other associated factors
(Makerere University, 2022-12)
Introduction; In 2020, there were about 1.75 million adolescents living with HIV (ALWHIV) around the world. Approximately 1.5 million HIV-infected adolescents were from Sub-Saharan Africa, and by the end of 2019, about 7% ...
Neutrophil gelatinase-associated lipocalin is elevated in children with acute kidney injury and sickle cell anemia, and predicts mortality
(Elsevier, 2022)
Urine neutrophil gelatinase-associated lipocalin (NGAL) is a biomarker of acute kidney injury that has been adapted to a urine dipstick test. However, there is limited data on its use in low and-middle-income countries ...
Low-level viraemia: An emerging concern among people living with HIV in Uganda and across sub-Saharan Africa
(AOSIS, 2022)
Attaining viral load (VL) suppression for over 95% of the people living with HIV on antiretroviral therapy is a fundamental step in enabling Uganda and other sub-Saharan African countries to achieve global Sustainable ...
Outcomes and predictors of survival among children with hodgkin lymphoma at Uganda Cancer Institute
(Makerere University, 2022-11)
Background: Hodgkin Lymphoma (HL) is one of the most curable childhood malignancies. HL represents 6% of all childhood cancers and has an incidence rate of 12 cases/million/year in the 0–14-year age group worldwide It has ...
Exploring the global genetic diversity of P. falciparum Pf113 malaria vaccine candidate gene
(Makerere University, 2022)
The malaria disease burden is still of great concern especially in sub-Saharan Africa among children below the age of 5 years. Evolution of the P. falciparum parasite in response to intervention measures as well as the ...
Pharmacokinetic/pharmacodynamic Modeling to optimize efavirenz dosing in HIV/AIDs infected children from Sub-Saharan Africa.
(Makerere University, 2022-12)
Aim:Using a model‐based approach, the efavirenz steady‐state pharmacokinetics in Sub-Saharan African children is characterized, quantifying demographic and genotypic effects on the drug's disposition. Simulations are also ...
Revalence and factors associated with hyperuricaemia among diabetes mellitus patients at Kiruddu National Referral Hospital, Uganda
(Makerere University, 2022-08)
Background: The prevalence of hyperuricemia is increasing around the world, especially among patients with diabetes mellitus (DM). Hyperuricemia leads to worsening hyperglycemia, and this accelerates the progression of ...
Association between indoor residual spraying and pregnancy outcomes: a quasi-experimental study from Uganda
(Oxford University Press, 2022)
Background: Malaria is a risk factor for adverse pregnancy outcomes. Indoor residual spraying with insecticide (IRS) reduces malaria infections, yet the effects of IRS on pregnancy outcomes are not well established. We ...