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Simulation of clonal expansion and latent HIV reservoir size prediction using machine learning in virally suppressed individuals in Uganda
(Makerere University, 2022-07)
Background: HIV can survive as pro-viruses that do not undergo transcription mostly within resting memory CD4+ T cells despite prolonged antiretroviral therapy (ART). This Latent Viral Reservoir (LVR) has an extremely long ...
Low-level viraemia: An emerging concern among people living with HIV in Uganda and across sub-Saharan Africa
(AOSIS, 2022)
Attaining viral load (VL) suppression for over 95% of the people living with HIV on antiretroviral therapy is a fundamental step in enabling Uganda and other sub-Saharan African countries to achieve global Sustainable ...
Low-abundance drug resistant variant patterns among HIV-1 patients with virological failure in Uganda
(Makerere University, 2022-03)
Background: The emergence and spread of antiretroviral drug resistant HIV-1 variants is one
of the major factors responsible for therapeutic failure in persons living with HIV (PLWH) as
it jeopardizes the efforts to ...
Suspected adverse drug reactions of isoniazid preventive therapy in HIV-positive patients at three regional hospitals: prevalence, associated factors, management and reporting
(Makerere University, 2021-11)
Background
Tuberculosis (TB) is the 10th leading cause of death globally and the leading cause of death from a single infectious agent among people living with HIV (PLHIV). Uganda is among the 30 high burden TB countries ...
Prevalence and factors associated with dyslipidemia among adult patients on dolutegravir based antiretroviral regimen at Mengo Hospital, A cross-sectional study
(Makerere University, 2022-12)
Introduction: Dolutegravir (DTG) based anti-retroviral therapy (ART) regimen has been rolled out in Uganda as the preferred first- and second-line treatment option in the management of Human Immunodeficiency Virus (HIV). ...
Dual contraceptive utilization and associated factors among women living with the Human Immunodeficiency Virus (HIV) at Kawempe National Referral Hospital, Kampala Uganda
(Makerere University, 2022-12)
Introduction: Dual contraceptive utilization (DCU) maximizes the prevention of unintended pregnancies and sexually transmitted infections including HIV infection. In Uganda DCU among women living with HIV (WLHIV) is low. ...
Viral load suppression among aAdolescents in HIV Care within primary health care facilities in Lubaga Division, Kampala Capital City Authority
(Makerere University, 2022-12)
Background: Adolescents on ART should virally suppress within six months to live longer, boost immune system and reduce risk of HIV transmission . This study investigated VLS among adolescents in HIV care in primary ...
HIV viral load suppression and associated factors among people with mental disorders at Butabika Hospital and Mulago ISS Clinics: A mixed methods study
(Makerere University, 2022-12)
INTRODUCTION
In 2017 Uganda adopted the universal test and treat (UTT) guidelines. According to the UTT guidelines, people who test positive for HIV should be immediately initiated on antiretroviral therapy (ART) regardless ...
Time to non-retention in HIV care and associated factors among assisted partner notification HIV+ patients enrolled in care in Hoima and Kiboga Districts, Uganda
(Makerere university, 2022-12)
Introduction:
Globally, by the end of the year 2020, enormous strides had been made toward the achievement of the UNAIDS 90-90-90 HIV testing and treatment targets that were set in 2014. Such targets had spelled out that ...
Clinical, immunological, virological characteristics, and hospitalisation outcomes of patients admitted to Kiruddu Hospital with advanced HIV disease
(Makerere University, 2022-08)
Introduction
Nearly four decades after the first case of AIDS was described, the global number of AIDS related deaths is not declining as expected to meet elimination targets, especially in sub-Saharan Africa where the ...