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Presumptive treatment with sulphadoxine-pyrimethamine versus weekly chloroquine for malaria prophylaxis in children with sickle cell anaemia in Uganda: a randomized controlled trial
(BioMed Central, 2009-10-24)
Background: Malaria carries high case fatality among children with sickle cell anaemia. In Uganda, chloroquine is used for prophylaxis in these children despite unacceptably high levels of resistance. Intermittent presumptive ...
Complexity of plasmodium falciparum clinical samples from Uganda during short-term culture.
(University of Chicago Press, 2008-08-22)
We cultured Plasmodium falciparum parasites from 98 Ugandan children with malaria and determined the complexity of infection (COI) on the basis of msp-2 polymorphisms daily for 9 days. The mean COI decreased during culture ...
Prevalence and atiology of bacteraemia in severely malnourished children attending Mulago Hospital
(2002)
BACKGROUND:
Severe malnutrition is a major cause of childhood morbidity and mortality especially in developing counties. Severe malnutrition affects 7% of Uganda children below 5 years. During a 3 months study period, 226 ...
Selection of parasites with diminished drug susceptibility by amodiaquine-containing antimalarial regimens in Uganda.
(Oxford University Press, 2009-11-04)
Background. Amodiaquine (AQ) is paired with artesunate (AS) or sulfadoxine-pyrimethamine (SP) in recommended antimalarial regimens. It is unclear how readily AQ resistance will be selected with combination chemotherapy. ...
Variations of plasma concentrations of artemether-lumefantrine with age and weight in children presenting with uncomplicated malaria at Mulago Hospital.
(2009-10)
INTRODUCTION:
Malaria is still one of the main causes of mortality and morbidity in Ugandan children with the under 5 year mortality rate of 136/100,000. ACTs are the first line of treatment of uncomplicated malaria. ...
Socioeconomic predictors of cognition in Ugandan children: implications for community interventions
(Public Library of Science, 2009)
Background: Several interventions to improve cognition in at risk children have been suggested. Identification of key
variables predicting cognition is necessary to guide these interventions. This study was conducted to ...
Nutritional status and associated tactors among children aged 6 weeks-23 months attending the young child clinic in Lira Regional Referral Hopital
(2008)
Introduction: Child malnutrition is the component of child morbidity that is most studied yet malnutrition still remains a challenge. Despite the fact that malnutrition measured in terms of population averages has greatly ...
Prevalence and factors associated with rotavirus infection among children admitted with acute care diarrhoea in Mulago hospital
(2007-07)
BACKGROUND:
Rotavirus remains the most common cause of severe dehydration diarrhoea among children worldwide. By five years of age, almost all children will have had an episode of rotavirus gastroenteritis. Children in ...
The diagnosis of childhood tuberculosis in an HIV-endemic setting and the use of induced sputum
(International Union Against Tuberculosis and Lung Disease, 2005)
Setting: A hospital in the capital city of Uganda. Objectives: To determine the proportion of positive induced sputum cultures among probable childhood tuberculosis (TB) cases, to describe the laboratory and radiological ...
Artemether-lumefantrine versus dihydroartemisinin-piperaquine for treatment of malaria: a randomized trial.
(2007-05-18)
Objectives: To compare the efficacy and safety of artemether-lumefantrine (AL) and dihydroartemisinin-piperaquine (DP) for treating uncomplicated falciparum malaria in Uganda. Design: Randomized single-blinded clinical ...