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Quality of data collection in a large HIV observational clinic database in sub-Saharan Africa: implications for clinical research and audit of care
(BioMed Central, 2011)
Background: Observational HIV clinic databases are now widely used to answer key questions related to HIV care and treatment, but there has been no systematic evaluation of their quality of data. Our objective was to ...
Potential impact of task-shifting on costs of antiretroviral therapy and physician supply in Uganda
(BMC Health Services Research, 2009-01-09)
Background Lower-income countries face severe health worker shortages. Recent evidence suggests that this problem can be mitigated by task-shifting—delegation of aspects of health care to less specialized health workers. ...
Is it safe to switch from stavudine to zidovudine after developing symptomatic hyperlactatemia?
(African Health Sciences, 2008-06)
Introduction: In resource limited settings patients on antiretroviral treatment who develop stavudine induced hyperlactatemia are often switched to zidovudine on the basis of published studies that demonstrate that this ...
Evaluation of portable point-of-care CD4 counter with high sensitivity for detecting patients eligible for antiretroviral therapy
(Public Library of Science, 2012-04-19)
Background: Accurate, inexpensive point-of-care CD4+ T cell testing technologies are needed that can deliver CD4+ T cell results at lower level health centers or community outreach voluntary counseling and testing. We ...
Symptomatic hyperlactatemia associated with nucleoside analogue reverse-transcriptase inhibitor use in HIV-infected patients: a report of 24 cases in a Resource-Limited Setting (Uganda).
(University of Chicago Press, 2007)
We describe 24 Ugandan patients with human immunodeficiency virus infection who developed symptomatic hyperlactatemia associated with the use of nucleoside analogues. All patients were receiving combination therapy that ...
Rifampicin for continuation phase tuberculosis treatment in Uganda: a cost-effectiveness analysis
(Public Library of Science, 2012-06)
Background: In Uganda, isoniazid plus ethambutol is used for 6 months (6HE) during the continuation treatment phase of new tuberculosis (TB) cases. However, the World Health Organization (WHO) recommends using isoniazid ...
Integration of HIV and TB services results in improved TB treatment outcomes and earlier prioritized ART initiation in a large urban HIV clinic in Uganda
(Lippincott, Williams & Wilkins, 2012-06-01)
Background: The World Health Organization recommends that treatment of tuberculosis ...
Sub-optimal CD4 reconstitution despite viral suppression in an urban cohort on Antiretroviral Therapy (ART) in sub-Saharan Africa: Frequency and clinical significance
(BioMed Central, 2008-10)
Background: A proportion of individuals who start antiretroviral therapy (ART) fail to achieve adequate CD4 cell reconstitution despite sustained viral suppression. We determined the frequency and clinical significance of ...
Symtomatic hyperlactatemia associated with nucleoside analogue reverse-transcriptase inhibitor use in HIV-infected patients: a report of 24 cases in a resource limited setting (Uganda).
(University of Chicago Press, 2007-04-19)
We describe 24 Ugandan patients with human immunodeficiency virus infection who developed symptomatic hyperlactatemia associated with the use of nucleoside analogues. All patients were receiving combination therapy that ...
Can response of a pruritic papular eruption to antiretroviral therapy be used as a clinical parameter to monitor virological outcome?
(Lippincott Williams & Wilkins, 2008)
Background: A pruritic papular eruption (PPE) is a common skin manifestation observed in 12–46% of persons with HIV infection living in tropical countries. Objective: To determine whether PPE responds to HAART and whether ...