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Cotrimoxazole Prophylaxis specifically selects for Cotrimoxazole resistance in Streptococcus mutans and Streptococcus sobrinus with varied Polymorphisms in the target genes folA and folP
(Hindawi Publishing Corporation, International Journal of Microbiology, 2012)
The selection of antibiotic resistance by cotrimoxazole prophylaxis was evaluated, and we characterized the mechanism of cotrimoxazole resistance in Streptococcus mutans and Streptococcus sobrinus. In vitro susceptibility ...
Co-trimoxazole resistance of streptococcus pnemoniae and commensal strptococci from Kampala, Uganda
(2007)
Trimethoprim-sulfamethoxazole (co-trimoxazole) is used frequently for people living with HIV/AIDS in Africa. In this study, the prevalence and mechanisms of resistance to sulfonamides and trimethoprim in commensal oral ...
Sulfadoxine-pyrimethamine plus chloroquine or amodiaquine for uncomplicated falciparum malaria: a randomized, multisite trial to guide national policy in Uganda
(2005)
The use of combinations of inexpensive drugs for the treatment of malaria in Africa has been proposed as an interim policy while awaiting the widespread availability of more effective regimens. We compared sulfadoxinepyrimethamine ...
Artemisinin versus nonartemisinin combination therapy for uncomplicated malaria: randomized clinical trials from four sites in Uganda
(Public Library of Science, 2005-07)
Background Drug resistance in Plasmodium falciparum poses a major threat to malaria control. Combination antimalarial therapy including artemisinins has been advocated recently to improve efficacy and limit the spread of ...