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Prevalence, pattern and factors associated with liver enzyme elevation among HIV-infected patients admitted in Kiruddu National Referral Hospital
(Makerere University, 2022-12-18)
Background: Globally, mortality and morbidity among Human Immunodeficiency Virus (HIV)-infected patients have tremendously improved over the years in this post- Highly Active Anti-retroviral Therapy (HAART) era. However, ...
Access to anti-hypertensive and anti-diabetic medications amongst people living with HIV in Soroti District, Eastern Uganda
(Makerere University, 2022-12)
Background:
Access to anti-diabetic and anti-hypertensive medicines is one of the factors that needs to be addressed so as to ensure continuous availability of affordable quality of care to HIV clients living with ...
Whole exome sequencing uncovers genetic predisposition to pediatric HIV disease progression and hyperhemolysis syndrome
(Makerere University, 2022-07)
Background: Populations of African ancestry hold a disproportionate burden of infectious and non-infectious diseases. Genetic variants, with population allele frequencies ranging from rare to common variants, are believed ...
Low-level viraemia: An emerging concern among people living with HIV in Uganda and across sub-Saharan Africa
(AOSIS, 2022)
Attaining viral load (VL) suppression for over 95% of the people living with HIV on antiretroviral therapy is a fundamental step in enabling Uganda and other sub-Saharan African countries to achieve global Sustainable ...
Low-abundance drug resistant variant patterns among HIV-1 patients with virological failure in Uganda
(Makerere University, 2022-03)
Background: The emergence and spread of antiretroviral drug resistant HIV-1 variants is one
of the major factors responsible for therapeutic failure in persons living with HIV (PLWH) as
it jeopardizes the efforts to ...
Suspected adverse drug reactions of isoniazid preventive therapy in HIV-positive patients at three regional hospitals: prevalence, associated factors, management and reporting
(Makerere University, 2021-11)
Background
Tuberculosis (TB) is the 10th leading cause of death globally and the leading cause of death from a single infectious agent among people living with HIV (PLHIV). Uganda is among the 30 high burden TB countries ...
Factors influencing utilization of paediatric HIV care and treatment services in Njombe Region, Tanzania
(Makerere University, 2014)
Introduction and Background: HIV/AIDS is one of the major cause of child death in Tanzania (UNICEF, 2012). However, utilization of HIV care and treatment services is very low in this setting (NACP, 2013). This study therefore ...
Prevalence and factors associated with dyslipidemia among adult patients on dolutegravir based antiretroviral regimen at Mengo Hospital, A cross-sectional study
(Makerere University, 2022-12)
Introduction: Dolutegravir (DTG) based anti-retroviral therapy (ART) regimen has been rolled out in Uganda as the preferred first- and second-line treatment option in the management of Human Immunodeficiency Virus (HIV). ...
Dual contraceptive utilization and associated factors among women living with the Human Immunodeficiency Virus (HIV) at Kawempe National Referral Hospital, Kampala Uganda
(Makerere University, 2022-12)
Introduction: Dual contraceptive utilization (DCU) maximizes the prevention of unintended pregnancies and sexually transmitted infections including HIV infection. In Uganda DCU among women living with HIV (WLHIV) is low. ...
Effect of hydrocortisone hormone on in-vitro reactivation of HIV-1 reservoirs
(Makerere University, 2022-07)
The persistence of the HIV-1 reservoir in infected individuals represents a major hurdle to the development of a cure and complete eradication of HIV-1 infection. Stress hormones have also been shown to modulate immune ...