Browsing College of Health Sciences (CHS) by Subject "SARS-CoV-2"
Now showing items 1-5 of 5
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African human variants that potentially impact the outcome of SARS-CoV-2 infection
(Makerere University, 2023-11-15)Introduction: The SARS-CoV-2 pandemic has had an unprecedented global impact, resulting in millions of confirmed cases and deaths. However, the severity and death rates varied among different ethnicities and geographical ... -
Early cytokine profiles associated with mild and asymptomatic COVID-19 disease severity in Uganda
(Makerere University, 2022-12-20)Emergence of the Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) constituted a global health threat of highly impactful and pandemic proportions. However, low COVID-19 disease severity was observed in Uganda ... -
Evaluation of pre-existing cross reactive cellular immune responses to SARS-CoV-2 in Uganda
(Makerere University, 2022-12)Background: A low severity of COVID-19 disease has been reported in the Africa population more so in Uganda as compared to other regions like Europe, America and West Pacific. Over 169,996 people have been infected with ... -
Genomic characterization of SARS-CoV-2 from Uganda using MinION Nanopore sequencing
(Makerere University, 2022-12)Background: The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an enveloped virus with a single-stranded, positive-sense RNA genome of approx. 29.9 kilobase pairs. The genome undergoes genetic mutations ... -
Seroprevalence and factors associated with SARS-CoV-2 Seropositivity among children in 32 Districts in Uganda
(Makerere University, 2023-10-16)Although the epidemiology and clinical presentation of SARS-CoV-2 is well described in adult population, the SARS-CoV-2 infection epidemiology in the pediatric population, especially in the sub-Saharan Africa is not well ...