Browsing College of Health Sciences (CHS) by Subject "TB"
Now showing items 21-40 of 57
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Factors associated with health seeking behaviour of pulmonary tuberculosis patients at Mulago National Referral Tuberculosis Treatment Centre.
(2002-06)SETTING: The study was carried out at Mulago National Referral Tuberculosis Treatment Centre, Kampala, Uganda, East Africa. OBJECTIVE: The study aimed at assessing factors associated with the health-seeking behavior of ... -
Factors associated with missed opportunities in TB investigation in public facilities in Wakiso District
(Makerere University, 2018-11)Introduction Tuberculosis (TB) is a major public health problem in Uganda. The prevalence of TB in Uganda is 273/100,000. Despite the implementation of several interventions to increase TB case detection in Uganda such ... -
Factors associted with defaulting on tuberculosis treatment among HIV infected patients at the Infectious Disease Institute Clinic, Kampala, Uganda
(2009-10)INTRODUCTION: Default from TB treatment poses challenges to TB control including the emergence of drug resistant TB, Higher rates of relapse and retreatment and increased treatment expense and need for human resources. ... -
Factors influencing defaulting from tuberclosis treatment in Masaka District
(2004-06)Background: Tuberculosis is a worldwide burden of infectious diseases About 2 Billion People are infected with TB every year and 3 Million people die. TB defaulting has been estimated to be 50-60% in Masaka district. ... -
Health service delay and associated factors among pulmonary tuberculosis patients presenting to Mulago Hospital: a cross sectional study.
(2009-10)Delay in the diagnosis of pulmonary tuberculosis (PTB) is common in many countries in sub-Saharan Africa. Timely diagnosis of active TB is particularly crucial to minimise not only morbidity and mortality in the community, ... -
Health-related quality of life among smear positive pulmonary tuberculosis patients in Mbale District, Uganda
(Makerere University, 2014-11)Introduction: Drug therapy prevents tuberculosis (TB) spread, morbidity and mortality but it affects the patients’ health-related quality of life (HRQoL). Currently, TB case management guidelines focus so much attention ... -
Healthcare workers’ knowledge, attitudes, and practices towards multi-drug resistant tuberculosis, Arua District, Uganda
(Makerere University, 2023)Background: Multidrug-resistant TB (MDR-TB) remains a public health crisis and a health security threat. The incidence of MDR TB in Uganda is 3.2 cases per 100,000 population. Cumulatively the MDR TB unit in the Arua ... -
The impact of HIV status on diagnosis of pulmonary tuberculosis in Mbale District.
(2002)SETTING: This study was carried out in Mbale regional hospital wghich is found on the eastern part of the country. It was a hospital-based cross-sectional descriptive study of newly diagnosed PTB patients aged 15 years ... -
In vitro activity of mycobacteriophages against Mycobacterium tuberculosis biofilms
(Makerere University, 2021-03)Tolerance of Mycobacterium tuberculosis to antibiotics has been associated with its tendency to grow in cell aggregates known as biofilms. These biofilms consist of layers of cells covered by a lipid-rich extracellular ... -
In vivo PPD reactivity and associated factors among HIV positive patients on HAART at the Makerere University Infectious Diseases Clinic.
(2009-08)BACKGROUND: It is estimated that a third of the world’s population is infected with tuberculosis (TB). This epidemic is fueled by HIV, with reactivation rates of 8-10% / year and overall lifetime risk of 30% in HIV ... -
Incidence and factors associated with late sputum culture conversion among multi-drug resistant tuberculosis patients on treatment at Mulago Hospital
(Makerere University, 2021-03-25)Introduction: Tuberculosis (TB) remains one of the most common causes of death from an infectious disease. Late sputum culture conversion of Multi-Drug Resistant Tuberculosis (MDR-TB) patients poses a risk for poor treatment ... -
Incidence and predictors of mortality and the effect of tuberculosis immune reconstitution inflammatory syndrome in a cohort of TB/HIV patients commencing antiretroviral therapy
(Lippincott Wilkins & Williams, 2011)Background: Tuberculosis-HIV (TB-HIV) coinfection remains an important cause of mortality in antiretroviral therapy (ART) programs. In a cohort of TB-HIV–coinfected patients starting ART, we examined the incidence and ... -
Incidence and predictors of two months’ sputum non follow-up and patients’ perceived quality of care among tuberculosis patients, Hoima District
(Makerere University, 2019-06)Introduction: The World Health Organization and Ministry of health recommend monitoring of tuberculosis patients on treatment for progress. Provision of sufficiently high tuberculosis care quality is necessary to achieve ... -
Mycobacterium tuberculosis associated immune activation, inhibition and exhaustion profiling to predict active tuberculosis disease among presumptive tuberculosis participants and monitor anti-tuberculosis treatment response.
(Makerere University, 2023)Globally, tuberculosis (TB) is the leading cause of mortality and morbidity especially among resource-limited populations including Uganda. This statistic is greatly fueled by the delay in diagnosis of the disease and ... -
Mycobacterium tuberculosis expression of Antigen 85B (Ag85B) in different culture conditions
(Makerere University, 2022-03)Background: : Secretion of specific proteins by Mycobacterium tuberculosis contributes to pathogenesis and immune responses in tuberculosis disease yet the quantification of these secreted proteins in-vitro are poorly ... -
Non-linear mixed effects modeling of liver function biomarkers in TB-HIV patients co-treated with Rifampicin and Efavirenz based regimens
(2013-11)Introduction Survival has improved as a result of improved HIV therapy but liver disease remains a critical problem in HIV patients. HIV disease, ART and Tuberculosis treatments have all been documented to cause liver ... -
Nucleic acid amplification tests for diagnosis of smear-negative TB in a high HIV prevalence setting: a prospective cohort study
(Public Library of Science, 2011-01)Background: Nucleic acid amplification tests are sensitive for identifying Mycobacterium tuberculosis in populations with positive sputum smears for acid-fast bacilli, but less sensitive in sputum-smear-negative populations. ... -
The past and present radiographic manifestations of pulmonary tuberculosis at Mulago Hospital
(1989-04)A cross-sectional study of the chest radiographs of adult tuberculosis patients, seen at Mulago Hospital, in 1972, 1979 and 1988 was carried out between August and December 1988. The aim of the study was to determine the ... -
Performance evaluation of the Uganda National Algorithm for Diagnosis of tuberculosis in children at Mulago National Referral Hospital-Kampala, Uganda
(Makerere University, 2023)Background Diagnosing childhood tuberculosis (TB) is a challenge, this led the Uganda national tuberculosis control program (NTLP) to develop a clinical treatment decision algorithm for children. However, there is limited ... -
Performance of the tuberculosis specimen referral system in the South Western TB zone of Uganda
(Makerere University, 2017-02)Background: Multidrug resistant tuberculosis (MDR-TB) stands at 12.5% in Uganda among the retreatment TB cases. In an effort to accelerate the WHO-recommended MDR-TB diagnosis and surveillance, the Uganda NTLP in 2008 ...