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Urban movement and alcohol intake strongly predict defaulting from tuberculosis treatment: an operational study
(Public Library of Science, 2012-05-02)
Background:High levels of defaulting from treatment challenge tuberculosis control in many African cities. We assessed defaulting from tuberculosis treatment in an African urban setting.
Methods: An observational study ...
Medical male circumcision for HIV/AIDS prevention in Uganda: the cost of disposable versus re-usable circumcision kits
(Tropical Doctor, 2012-01-01)
We evaluated the cost implications of medical male circumcisions for HIV prevention when performed using re-usable equipment that is sterilized after each use versus using single-use disposal kits. In Uganda, a re-usable ...
Integrating cryptococcal antigen screening andpPre-emptive treatment into routine HIV care
(Lippincott, Williams & Wilkins, 2012-04-15)
Cryptococcal meningitis is a leading cause of death in AIDS patients in sub-Saharan Africa. Cryptococcal antigen (CRAG) can be detected weeks before onset of symptoms, and those who are asymptomatic but CRAG positive have ...
The epidemiology and clinical correlates of HIV-1 co-receptor tropism in non-subtype B infections from India, Uganda and South Africa
(Journal of the International AIDS Society, 2012-01-26)
Background: The introduction of C-C chemokine receptor type-5 (CCR5) antagonists as antiretroviral therapy has led to the need to study HIV co-receptor tropism in different HIV-1 subtypes and geographical locations. This ...
An Autopsy Study Describing Causes of Death and Comparing Clinico-Pathological Findings among Hospitalized Patients in Kampala, Uganda
(PLoS ONE, 2012-03-14)
Background: Information on causes of death in HIV-infected patients in Sub-Saharan Africa is mainly derived from observational cohort and verbal autopsy studies. Autopsy is the gold standard to ascertain cause of death. ...
Lopinavir/ritonavir significantly influences pharmacokinetic exposure of artemether/lumefantrine in HIV-infected Ugandan adults
(Journal of Antimicrobial Chemotherapy, 2012-02-08)
Background: Treatment of HIV/malaria-coinfected patients with antiretroviral therapy (ART) and artemisininbased combination therapy has potential for drug interactions. We investigated the pharmacokinetics of artemether, ...
Pharmacokinetic interactions between antiretroviral drugs and herbal medicines
(British Journal of Hospital Medicine, 2012-03-13)
Prevalence and factors associated with cryptococcal antigenemia among severely immunosuppressed HIV-infected adults in Uganda: a cross-sectional study
(Journal of the International AIDS Society, 2012-03-14)
Background: Cryptococcal infection is a common opportunistic infection among severely immunosuppressed HIV patients and is associated with high mortality. Positive cryptococcal antigenemia is an independent predictor of ...
Low prevalence of pneumocystis jirovecii lung colonization in Ugandan HIV-infected patients hospitalized with non-Pneumocystis pneumonia
(SciVerse ScienceDirect, 2012-02-15)
Pneumocystis jirovecii is an important opportunistic infection in human immunodeficiency virus (HIV)–infected patients. In the developed world, P. jirovecii epidemiology is marked by frequent colonization in immunosuppressed ...
Sub-optimal vitamin B-12 levels among ART-Naïve HIV positive individuals in an urban cohort in Uganda
(Public Library of Science, 2012-07-02)
Malnutrition is common among HIV-infected individuals and is often accompanied by low serum levels of micronutrients. Vitamin B-12 deficiency has been associated with various factors including faster HIV disease progression ...