Browsing Infectious Diseases Institute (IDI) Collections by Subject "Pharmacokinetics"

Now showing items 1-3 of 3

    • Antiretroviral therapy in developing countries: pharmacologic considerations 

      Lamorde, Mohammed; Byakika-Kibwika, Pauline; Merry, Concepta (Lippincott Williams & Wilkins, 2008)
      Purpose of review This article reviews recent studies in the field of clinical pharmacology of antiretroviral drugs and highlights the relevance of the findings to clinical practice in developing countries. Recent findings ...

    • Effect of food on the steady-state pharmacokinetics of tenofovir and emtricitabine plus efavirenz in Ugandan adults 

      Lamorde, Mohammed; Byakika-Kibwika, Pauline; Tamale, William S.; Kiweewa, Francis; Ryan, Mairin; Amara, Alieu; Tjia, John; Back, David; Khoo, Saye; Boffito, Marta; Kityo, Cissy; Merry, Concepta (Hindawi Publishing Corporation, 2012-02-20)
      We investigated the effect of food on the steady-state pharmacokinetics of a proprietary fixed-dose combination (FDC) tablet containing tenofovir disoproxil fumarate (TDF)/emtricitabine/efavirenz. Fifteen Ugandan HIV-1 ...

    • Pharmacokinetics and pharmacodynamics of intravenous artesunate during severe malaria treatment in Ugandan adults 

      Byakika-Kibwika, Pauline; Lamorde, Mohammed; Mayito, Jonathan; Nabukeera, Lillian; Mayanja-Kizza, Harriet; Katabira, Elly; Hanpithakpong, Warunee; Obua, Celestino; Pakker, Nadine; Lindegardh, Niklas; Tarning, Joel; de Vries, Peter J.; Merry, Concepta (BioMed Central, 2012-04-27)
      Background: Severe malaria is a medical emergency with high mortality. Prompt achievement of therapeutic concentrations of highly effective anti-malarial drugs reduces the risk of death. The aim of this study was to assess ...