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Theoretical basis for reducing time-lines to the determination of positive Mycobacterium tuberculosis cultures using thymidylate kinase (TMK) assays
(BioMed Central, 2009-03-18)
Background: In vitro culture of pathogens on growth media forms a "pillar" for both infectious disease diagnosis and drug sensitivity profiling. Conventional cultures of Mycobacterium tuberculosis (M.tb) on Lowenstein ...
Searching for new clues about the molecular cause of endomyocardial fibrosis by way of in SilicoProteomics and analytical chemistry
(Public Library of Science, 2009-10-12)
Background: Endomyocardial Fibrosis (EMF) –is a chronic inflammatory disease of the heart with related pathology to that of late stage Chaga’s disease. Indeed, both diseases are thought to result from auto-immune responses ...
In silico evidence for the species-specific conservation of mosquito retroposons: implications as a molecular biomarker
(BioMed Central, 2009)
Background: Mosquitoes are the transmissive vectors for several infectious pathogens that affect man. However, the control of mosquitoes through insecticide and pesticide spraying has proved difficult in the past. We ...