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Low-abundance drug resistant variant patterns among HIV-1 patients with virological failure in Uganda
(Makerere University, 2022-03)
Background: The emergence and spread of antiretroviral drug resistant HIV-1 variants is one
of the major factors responsible for therapeutic failure in persons living with HIV (PLWH) as
it jeopardizes the efforts to ...
Correlation of plasma HIV-1 p24 antigen levels with viral load in samples of HIV positive patients on ART in Uganda
(Makerere University, 2022-12)
Globally, a total of 38.0 million people living with HIV, of which 1.7 million people became newly infected with HIV in 2019. Additionally, an average of 690,000 people died from AIDS-related illnesses in 2019, and 26 ...
HLA Class I and Pediatric HIV disease progression in Botswana and Uganda
(Makerere University, 2023)
Sub-Saharan Africa remains the global epicenter of the HIV epidemic; more than 70% (25 million) of all people living with HIV/AIDS are in Africa. To end the global epidemic, finding an effective HIV vaccine remains a top ...
Reported adverse drug reactions of antiretroviral therapy generic formulations in Uganda
(Makerere Univesrity, 2023)
Background: Generic Antiretroviral drugs are commonly used in the developing countries and this has greatly contributed to the scaling up of ART. Generics vary in formulation including excipients, the production conditions ...