Browsing School of Bio-Medical Sciences (Bio-Medical) Collections by Author "Joloba, Moses L."
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Activation of the gab Operon in an RpoS-Dependent Manner by Mutations That Truncate the Inner Core of Lipopolysaccharide in Escherichia coli
Joloba, Moses L.; Clemmer, Katy M.; Sledjeski, Darren D.; Rather, Philip N. (American Society for Microbiology, 2004-12)The gab operon (gabDTPC) in Escherichia coli functions in the conversion of -aminobutyrate to succinate. One component of gab operon regulation involves the RpoS sigma factor, which mediates activation at high cell density. ... -
Differential prevalence of transporter polymorphisms in symptomatic and asymptomatic Falciparum Malaria Infections in Uganda
Tukwasibwe, Stephen; Mugenyi, Levi; Mbogo, George W.; Nankoberanyi, Sheila; Maiteki-Sebuguzi, Catherine; Joloba, Moses L.; Nsobya, Samuel L.; Staedke, Sarah G.; Rosenthal, Philip J. (Journal of Infectious Diseases, 2014)We explored associations between Plasmodium falciparum drug resistance–mediating polymorphisms and clinical presentations in parasitemic children enrolled in a cross-sectional survey in Tororo, Uganda, using a retrospective ... -
Evaluation of capilia TB assay for rapid identification of mycobacterium tuberculosis complex in BACTEC MGIT 960 and BACTEC 9120 blood cultures
Muchwa, Christopher; Akol, Joseph; Etwom, Alfred; Morgan, Karen; Orikiriza, Patrick; Mumbowa, Francis; Odong, Paul R.; Kateete, David P; Eisenach, Kathleen D.; Joloba, Moses L. (BioMed Central, 2012)Background: Capilia TB is a simple immunochromatographic assay based on the detection of MPB64 antigen specifically secreted by the Mycobacterium tuberculosis complex (MTC). Capilia TB was evaluated for rapid identification ... -
A metabolic biosignature of early response to anti-tuberculosis treatment
Mahapatra, Sebabrata; Hess, Ann M.; Johnson, John L.; Eisenach, Kathleen D.; DeGroote, Mary A.; Gitta, Phineas; Joloba, Moses L.; Kaplan, Gilla; Walz, Gerhard; Boom, W. Henry; Belisle, John T. (BMC Infectious Diseases, 2014)Background: The successful treatment of tuberculosis (TB) requires long-term multidrug chemotherapy. Clinical trials to evaluate new drugs and regimens for TB treatment are protracted due to the slow clearance of Mycobacterium ...