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dc.contributor.authorSacktor, Ned C.
dc.contributor.authorWong, Matthew
dc.contributor.authorNakasujja, Noeline
dc.contributor.authorSkolasky, Richard L.
dc.contributor.authorSelnes, Ola A.
dc.contributor.authorMusisi, Seggane
dc.contributor.authorRobertson, Kevin
dc.contributor.authorMcArthur, Justin C.
dc.contributor.authorRonald, Allan
dc.contributor.authorKatabira, Elly T.
dc.date.accessioned2013-07-05T07:15:22Z
dc.date.available2013-07-05T07:15:22Z
dc.date.issued2005
dc.identifier.citationSacktor, N.C., Wong, M., Nakasujja, N., Skolasky, R.L., Selnes, O.A., Musisi, S., Robertson, K., McArthur, J.C., Ronald, A., Katabira, E.T. (2005). The international HIV dementia scale: a new rapid screening test for HIV dementia. AIDS, 19en_US
dc.identifier.issn0269-9370
dc.identifier.urihttp://hdl.handle.net/10570/1717
dc.description.abstractObjective: HIV dementia is an important neurological complication of advanced HIV infection. The use of a cross-cultural screening test to detect HIV dementia within the international community is critical for diagnosing this condition. The objective of this study was to evaluate the sensitivity and specificity of a new screening test for HIV dementia, the International HIV Dementia Scale (IHDS) in cohorts from the US and Uganda. Design: Two cross-sectional cohort studies designed to evaluate for the presence of HIV dementia. Methods: Sixty-six HIV-positive individuals in the US and 81 HIV-positive individuals in Uganda received the IHDS and full standardized neurological and neuropsychological assessments. The sensitivity and specificity of varying cut-off scores of the IHDS were evaluated in the two cohorts. Results: In the US cohort, the mean IHDS score for HIV-positive individuals without dementia and with dementia were 10.6 and 9.3 respectively (P < 0.001). Using the cutoff of ≤ 10, the sensitivity and specificity for HIV dementia with the IHDS were 80% and 57% respectively in the US cohort, and 80% and 55% respectively in the Uganda cohort. Conclusions: The IHDS may be a useful screening test to identify individuals at risk for HIV dementia in both the industrialized world and the developing world. Full neuropsychological testing should then be performed to confirm a diagnosis of HIV dementia.en_US
dc.language.isoenen_US
dc.publisherLippincott Williams & Wilkinsen_US
dc.subjectHIV/AIDSen_US
dc.subjectDementiaen_US
dc.subjectScreening testen_US
dc.subjectUgandaen_US
dc.subjectInternationalen_US
dc.subjectScaleen_US
dc.titleThe international HIV dementia scale: a new rapid screening test for HIV dementia.en_US
dc.typeJournal article, peer revieweden_US


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