Makerere University Institutional Repository: Recent submissions
Now showing items 1-20 of 14111
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Prevalence, correlates, and predictive value of high-risk human papillomavirus mRNA detection in a community-based cervical cancer screening program in Western Uganda
(BMC, 2019)Background: New strategies are needed to combat the high incidence of cervical cancer in resource-limited settings such as sub-Saharan Africa. Screening for high-risk human papillomavirus (hrHPV) DNA is sensitive for ... -
Longer-term effectiveness of protease-inhibitor-based second line antiretroviral therapy in four large sub-Saharan African clinics
(Elsevier, 2019)Objectives: Data on the longer-term effectiveness of second line combination antiretroviral therapy (ART) in sub-Saharan Africa (SSA) are lacking. We sought to assess the probability and determinants of 2nd line ART ... -
Severity of post - operative knee stiffness and associated factors after surgical fixation of knee osseous injuries among adults at Mulago National Referral Hospital
(Makerere University, 2025-05)Background: Knee stiffness following surgical fixation of knee osseous injuries is a common and potential complication of surgery and rehabilitation with a global incidence of 4% to 38%. Even with the currently recommended ... -
The 14-day incidence and risk factors of gastrointestinal anastomotic leak among adult patients in Mulago Hospital, a prospective cohort study
(Makerere University, 2025)Background: Anastomotic leak is one of the most feared complications following gastrointestinal (GI) anastomotic surgery. It increases morbidity and mortality of patients undergoing GI surgery. Globally, the frequency of ... -
Prevalence and factors associated with hypertension among female nurses in private healthcare facilities in Jinja City
(Makerere University, 2024)Introduction: Hypertension affects 1.3 billion people globally and is predicted to rise to 1.56 billion by 2025, influenced by urbanization, sedentary lifestyles, and dietary shifts. Despite being essential to Uganda's ... -
Experiences of adult patients with cancer at a specialized cancer care facility in Uganda
(Wolters Kluwer Health Inc., 2025)Background: The experiences of adult cancer patients in low-income countries regarding health care and infrastructure are largely undocumented. This study aimed to describe the experiences of adult men and women receiving ... -
Adult patients with cancer in Uganda: validation of the tool, health-related quality of life, and patient experiences
(Makerere University, 2025)Background: This study aimed to assess the validity and reliability of the Luganda version of the tool used to measure health-related quality of life (HRQoL), specifically the European Organisation for Research and Treatment ... -
Prevalence and factors associated with pre-operative delays among neurotraumatic patients at Mulago National Referral Hospital: a cross-sectional study
(Makerere University, 2025)Introduction Neurotraumatic emergencies affect more than 10 million people globally with majority of them from sub-Saharan. Neurotraumatic emergencies present a challenge in emergency surgical care, demanding quick and ... -
An assessment of organisational knowledge management for health: a case study of a non-governmental organisation in Kampala, Uganda
(Makerere University, 2023)Knowledge management is a discipline that promotes an integrated approach to identifying, capturing, evaluating, retrieving, and sharing information assets. Knowledge management involves people, processes, and technology ... -
Prevalence and grading of meconium-stained amniotic fluid plus associated puerperal sepsis within 7 days at Kawempe National Referral Hospital.
(Makerere University, 2024)Background: Meconium-stained amniotic liquor remains both a maternal and neonatal health challenge globally as it is associated with higher rate of caesarean delivery, increased need for neonatal resuscitation, puerperal ... -
Short term outcomes of unstable pelvic fractures in adults treated at Mulago National Referral Hospital
(Makerere University, 2025)Introduction Pelvic fractures are perhaps the most severe & life-threatening musculoskeletal injuries, constituting about 1.5%–3% of all skeletal injuries. Despite their severity, unstable pelvic fractures can yield ... -
Molecular analysis of the MNS, KELL and LEWIS blood group systems in Sickle cell disease patients and blood donors from Kampala, Uganda
(Makerere University, 2025)Introduction: The Sickle cell disease (SCD) is a major red blood cell genetic disorder which is majorly managed by red blood cell transfusion that sometimes culminates into alloimmunisation. In 2016, the rate of alloimmunisation ... -
Adult patients with cancer in Uganda : validation of the tool, health-related quality of life, and patient experiences
(Makerere University, 2025)Background: This study aimed to assess the validity and reliability of the Luganda version of the tool used to measure health-related quality of life (HRQoL), specifically the European Organization for Research and Treatment ... -
Effect of bacteriophages against aeromonas hydrophila infections in tilapia oreochromis niloticus fingerlings and juvenile held in aquaria tanks
(Makerere University, 2023)This study assessed the effect of bacteriophages on Aeromonas hydrophilia infections in farmed fingerlings and juvenile tilapia fish group. The host bacteria (Aeromonas hydrophila) were revived and confirmed using biochemical ... -
NGO psychosocial support, unresolved grief and depression among AIDS orphans
(Makerere University, 2007)The objectives of this study were to examine the level of unresolved grief and depression between the supported and the non-supported AIDS orphans. Eighty AIDS orphans receiving support, and 80 who were not yet supported ... -
University chaplains and imams' roles on students' discipline: College of Education and External Studies, Makerere University.
(Makerere University, 2022-05-06)Discipline is a process of training or controlling an individual with an aim of making him/her to become compliant. Most successful societies or individuals have been disciplined. The vast enterprise of acquiring the ... -
Depressive and anxiety symptoms predict sustained quality of life deficits in HIV-positive Ugandan adults despite antiretroviral therapy
(Lippincott, 2016)The impact of psychosocial status at onset of antiretroviral therapy on changes in quality of life (QOL) and subjectively rated health (SRH) among adults on ART in resource-limited settings is poorly understood. Therefore, ... -
Improving the Sensitivity of the Xpert MTB/RIF Assay on sputum pellets by decreasing the amount of added sample reagent: a laboratory and clinical evaluation
(American Society for Microbiology, 2015)The Xpert MTB/RIF(Xpert) assay permits rapid near-patient detection of Mycobacterium tuberculosis in sputum; however, the test sensitivity remains suboptimal in paucibacillary specimens that are negative for acid-fast ... -
Treatment of HIV/AIDS. Do the dilemmas only increase?
(American Medical Association, 2004)Physicians and other health care professionals who treat patients with human immunodeficiency virus (HIV)/AIDS are confronted daily with complex challenges. Fortunately, several articles in this theme issue of JAMA on ... -
Assessing anaerobic co-digestion of faecal sludge with sugarcane press mud and water hyacinth for biogas and biofertilizer production
(Makerere University, 2025-04-22)In Uganda especially peri-urban areas, faecal sludge (FS) and agro-industry wastes are abundant, and their poor management poses environmental and public health risks. In a bid to find safe disposal and resource recovery, ...