Now showing items 1-2 of 2
Real-time imaging of the intracellular glutathione redox potential in the malaria parasite plasmodium falciparum
(Public Library of Science, 2013-12)
In the malaria parasite Plasmodium falciparum, the cellular redox potential influences signaling events, antioxidant defense, and mechanisms of drug action and resistance. Until now, the real-time determination of the redox ...
The molecular biology of sulfadoxine-pyrimethamine drug resistance of plasmodium falciparum strains in Uganda
(Makerere University, 2007-08)
In November of 2000, Uganda changed its anti-malarial policy to replace chloroquine (CQ) with a combination of CQ and sulphadoxine–pyrimethamine (SP) as the first line agents. The idea of the combination was to delay the ...