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http://hdl.handle.net/123456789/285
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| Title: | Treatment of East Coast Fever of cattle with a combination of Parvaquone and Frusmide |
| Authors: | Musoke, R. Azuba
Tweyongere, R.
Bizimenyara, E.
Waiswa, C.
Mugisha, A.
Biryomumaisho, S.
MacHardy, N. |
| Keywords: | East Cost Fever
Frusemide
Cattle
Cure rate
Parvaquone
Pulmonary oedema
Theieria parva
Treatment
Survival |
| Issue Date: | 2004 |
| Publisher: | Kluwer Academic Publishers |
| Citation: | Azuba Musoke, R., Tweyongere, R., Bizimenyara, E., Waiswa, C., Mugisha, A., Biryomumaisho, S., MacHardy, N., 2004. Treatment of East Coast Fever of cattle with a combination of Parvaquone and Frusmide. Tropical Animal Health and Production 36(3): 233-245 |
| Abstract: | Pulmonary oedema is a common sign of East Coast Fever (ECF Theileria parva infection) of cattle. A trial was conducted on farms in Uganda to compare a product containing both the antitheilerial compound parvaquone and the diuretic compound frusemide with one containing only parvaquone in the treatment of ECF. The trial involved 40 clinical cases of ECF, some of them complicated by other infections, in cattle of all ages and on several farms. Confirmed cases where treated with either parvaquone+ frusemide (P+F) or parvaquone alone (P). Survival after treatment with P+F was 77% compared with 71% with P. Five of the 10 fatalities were complicated cases. The cure rate for several but uncomplicated ECF was 89% with P+F and 40% with P. Parvaquone signs were resolved within 24-48 h after treatment with P+F and clinical recovery was noticeably more rapid than with P. The antiparasitic effect of the two treatments was similar. P+F could be particularly useful when reporting, diagnosis or laboratory confirmation of ECF is delayed because advanced cases are more likely to be encountered under these circumstances. |
| URI: | http://hdl.handle.net/123456789/285 |
| Appears in Collections: | Research Articles (Vet)
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| musoke-veterinary-res.pdf | Pulmonary oedema | 126Kb | Adobe PDF | View/Open |
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