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Please use this identifier to cite or link to this item: http://hdl.handle.net/123456789/1405

Title: Early-onset versus late-onset HIV-related secondary mania in Uganda.
Authors: Nakimuli-Mpungu, Etheldreda
Musisi, Seggane
Mpungu, Steven Kiwuwa
Katabira, Elly
Keywords: Highly Active Retroviral Therapy.
ARVs
HIV/AIDS
First-episode secondary mania
Early-onset mania
Late-onset mania
Issue Date: 2008
Citation: Nakimuli-Mpungu, E., Musisi, S., Mpungu, S.K., Katabira, E. (2008). Early-onset versus late-onset HIV-related secondary mania in Uganda. Psychosomatics, 49(6)
Abstract: Background: First-episode secondary mania in human immunodeficiency virus (HIV) infection has been described among samples of predominantly Caucasian, HIV-positive male patients in developed countries. Objective: The goal of this study was to compare the demographic and clinical characteristics of HIV-positive patients with early-onset and late-onset first-episode secondary mania in HIV infection. There were previous findings of an association between late-onset mania and severe cognitive impairment. Method: Subjects were HIV in patients with clinically confirmed mania, who received standard demographic, psychiatric, physical, and laboratory assessments. Early-onset patients had CD4 cell counts >200 mm3; late-onset patients had CD4 cell counts ≤200 mm.3 Results: There were no demographic or cognitive differences between early-onset and late-onset mania patients, and high rates of psychotic symptoms in both groups. However, late-onset patients had more manic symptoms. Conclusion: Late-onset HIV mania patients had more severe psychopathology and, thus, demonstrated a greater need for highly active retroviral therapy.
URI: http://hdl.handle.net/123456789/1405
ISSN: 0033-3182
Appears in Collections:Research Articles (Health-Sciences)

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