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http://hdl.handle.net/123456789/1405
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| Title: | Early-onset versus late-onset HIV-related secondary mania in Uganda. |
| Authors: | Nakimuli-Mpungu, Etheldreda Musisi, Seggane Mpungu, Steven Kiwuwa Katabira, Elly |
| Keywords: | Highly Active Retroviral Therapy. ARVs HIV/AIDS First-episode secondary mania Early-onset mania Late-onset mania |
| Issue Date: | 2008 |
| Citation: | Nakimuli-Mpungu, E., Musisi, S., Mpungu, S.K., Katabira, E. (2008). Early-onset versus late-onset HIV-related secondary mania in Uganda. Psychosomatics, 49(6) |
| Abstract: | Background: First-episode secondary mania in human immunodeficiency virus (HIV) infection has been described among samples of predominantly Caucasian, HIV-positive male patients in developed countries. Objective: The goal of this study was to compare the demographic and clinical characteristics of HIV-positive patients with early-onset and late-onset first-episode secondary mania in HIV infection. There were previous findings of an association between late-onset mania and severe cognitive impairment. Method: Subjects were HIV in patients with clinically confirmed mania, who received standard demographic, psychiatric, physical, and laboratory assessments.
Early-onset patients had CD4 cell counts >200 mm3; late-onset patients had CD4 cell counts ≤200 mm.3 Results: There were no demographic or cognitive differences between early-onset and late-onset mania patients, and high rates of psychotic symptoms in both groups. However, late-onset patients had more manic symptoms. Conclusion: Late-onset HIV mania patients had more severe psychopathology and, thus, demonstrated a greater need for highly active retroviral therapy. |
| URI: | http://hdl.handle.net/123456789/1405 |
| ISSN: | 0033-3182 |
| Appears in Collections: | Research Articles (Health-Sciences)
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| nakimuli-seggane-res-chs.pdf | | 51Kb | Adobe PDF | View/Open |
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