Browsing School of Bio-Medical Sciences (Bio-Medical) by Issue Date "2009"
Now showing items 1-4 of 4
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Emergence of sickle cell gene through migration and intermarriage: A case study
(Africa Journal of Animal and Biomedical Sciences, 2009)Sickle cell disease (SCD) is an inheritable disorder which is very common among persons of equatorial regions including Africa. The evolution of SCD is linked to malaria endemicity in which sickle cell traits are selected for ... -
A novel polymorphism in ABCB1 gene, CYP2B6*6 and sex predict single-dose efavirenz population pharmacokinetics in Ugandans
(The British Pharmacological Society, 2009)AIMS Efavirenz exhibits pharmacokinetic variability causing varied clinical response. The aim was to develop an integrated population pharmacokinetic/pharmacogenetic model and investigate the impact of genetic variations, ... -
A novel polymorphism in ABCB1 gene, CYP2B6*6 and sex predict single-dose efavirenz population pharmacokinetics in Ugandans
(Wiley-Blackwell, 2009)AIMS Efavirenz exhibits pharmacokinetic variability causing varied clinical response. The aim was to develop an integrated population pharmacokinetic/pharmacogenetic model and investigate the impact of genetic variations, ... -
Relationship between plasma levels of stavudine and self reported adherence rates to triomune in HIV/AIDS patients at the Joint Clinical Research Centre, Mengo Uganda.
(2009)INTRODUCTION: Adherence to antiretroviral therapy is mainly assessed by patient self reporting method in Uganda. The relationship between self reported adherence rates and plasma drug levels is not known. This study sought ...