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Now showing items 81-90 of 113
Tenofovir related renal toxicity monitoring in antiretroviral therapy (ART) accredited sites: A situational analysis for Uganda
(Makerere University, 2014-09)
Background: In Uganda, Tenofovir-based regimen is recommended as first line particularly for HIV/AIDS adult and adolescent patient and for option B+ in prevention of mother-to-child transmission (PMTCT). As a result of ...
Assessing quality of HIV Counselling services offered in public health facilities in Kampala
(Makerere University, 2016)
Introduction: HIV counselling has increasingly become available in public health facilities in Uganda. Counselling is a key component in HIV/AIDS prevention programs as an entry point into care, treatment and support ...
Simulation of clonal expansion and latent HIV reservoir size prediction using machine learning in virally suppressed individuals in Uganda
(Makerere University, 2022-07)
Background: HIV can survive as pro-viruses that do not undergo transcription mostly within resting memory CD4+ T cells despite prolonged antiretroviral therapy (ART). This Latent Viral Reservoir (LVR) has an extremely long ...
Prevalence, pattern and factors associated with liver enzyme elevation among HIV-infected patients admitted in Kiruddu National Referral Hospital
(Makerere University, 2022-12-18)
Background: Globally, mortality and morbidity among Human Immunodeficiency Virus (HIV)-infected patients have tremendously improved over the years in this post- Highly Active Anti-retroviral Therapy (HAART) era. However, ...
Access to anti-hypertensive and anti-diabetic medications amongst people living with HIV in Soroti District, Eastern Uganda
(Makerere University, 2022-12)
Background:
Access to anti-diabetic and anti-hypertensive medicines is one of the factors that needs to be addressed so as to ensure continuous availability of affordable quality of care to HIV clients living with ...
Whole exome sequencing uncovers genetic predisposition to pediatric HIV disease progression and hyperhemolysis syndrome
(Makerere University, 2022-07)
Background: Populations of African ancestry hold a disproportionate burden of infectious and non-infectious diseases. Genetic variants, with population allele frequencies ranging from rare to common variants, are believed ...
Prevalence and factors associated with viral suppression among HIV positive young adults receiving antiretroviral therapy in KCCA Clinics
(Makerere University, 2019-10)
Introduction: Over 30% of all new HIV infections globally are estimated to occur among young adults aged 15 to 24 years. Despite improving access to antiretroviral therapy (ART), young adults have been reported to have low ...
Low-level viraemia: An emerging concern among people living with HIV in Uganda and across sub-Saharan Africa
(AOSIS, 2022)
Attaining viral load (VL) suppression for over 95% of the people living with HIV on antiretroviral therapy is a fundamental step in enabling Uganda and other sub-Saharan African countries to achieve global Sustainable ...
Low-abundance drug resistant variant patterns among HIV-1 patients with virological failure in Uganda
(Makerere University, 2022-03)
Background: The emergence and spread of antiretroviral drug resistant HIV-1 variants is one
of the major factors responsible for therapeutic failure in persons living with HIV (PLWH) as
it jeopardizes the efforts to ...
Factors affecting antiretroviral therapy initiation among tuberculosis and human immunodeficiency virus co-infected patients at health facilities in Masaka district.
(2018-12-10)
Background: Evidence shows that infection with Human Immunodeficiency Virus (HIV)
increases the risk of tuberculosis (TB) infection following exposure to TB germs and HIV
also promotes progression of TB infection to ...