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Subclinical atherosclerosis among HIV-infected adults attending HIV/AIDS care at two large Ambulatory HIV clinics in Uganda
(PLOS One, 2014)
Background: The increased immune activation and inflammation of chronic HIV-infection and the characteristic dyslipidemias associated with HIV infection and antiretroviral therapy (ART) contribute to an increased risk of ...
Determinants of utilization of a no-cost HIV transition clinic: A cross-sectional study of young adults living with HIV/AIDS
(Adolescent Health, Medicine and Therapeutics, 2014)
There is minimal research that has been conducted among young adults to understand the determinants of the utilization of human immunodeficiency virus (HIV) health services in this population. The purpose of this study was ...
High CD56++CD16- natural killer (NK) cells among suboptimal immune responders after four years of suppressive antiretroviral therapy in an African adult HIV treatment cohort
(BMC Immunology, 2014)
Background: Up to 40% of HIV-infected individuals receiving Highly Active Antiretroviral Therapy (HAART) have poor CD4+ T-cell recovery. The role of natural killer (NK) cells in immune recovery during HAART is not well ...
Timing of Antiretroviral Therapy after Diagnosis of Cryptococcal Meningitis
(The New England Journal of Medicine, 2014)
Background
Cryptococcal meningitis accounts for 20 to 25% of acquired immunodeficiency
syndrome–related deaths in Africa. Antiretroviral therapy (ART) is essential for
survival; however, the question of when ART should ...
Belief in divine healing can be a barrier to antiretroviral therapy adherence in Uganda
(Lippincott Williams & Wilkins., 2007)
Although recent data suggest high levels of adherence to expanding antiretroviral therapy (ART) programmes in resource-limited settings, the culture- specific barriers to adherence are poorly understood. In a prospective ...
Timing of Antiretroviral Therapy after Diagnosis of Cryptococcal Meningitis
(Massachusetts Medical Society, 2014)
Background
Cryptococcal meningitis accounts for 20 to 25% of acquired immunodeficiency
syndrome–related deaths in Africa. Antiretroviral therapy (ART) is essential for
survival; however, the question of when ART should ...
Potential impact of task-shifting on costs of antiretroviral therapy and physician supply in Uganda
(BMC Health Services Research, 2009-01-09)
Background Lower-income countries face severe health worker shortages. Recent evidence suggests that this problem can be mitigated by task-shifting—delegation of aspects of health care to less specialized health workers. ...
Urban movement and alcohol intake strongly predict defaulting from tuberculosis treatment: an operational study
(Public Library of Science, 2012-05-02)
Background:High levels of defaulting from treatment challenge tuberculosis control in many African cities. We assessed defaulting from tuberculosis treatment in an African urban setting.
Methods: An observational study ...
The epidemiology and clinical correlates of HIV-1 co-receptor tropism in non-subtype B infections from India, Uganda and South Africa
(Journal of the International AIDS Society, 2012-01-26)
Background: The introduction of C-C chemokine receptor type-5 (CCR5) antagonists as antiretroviral therapy has led to the need to study HIV co-receptor tropism in different HIV-1 subtypes and geographical locations. This ...
Sub-optimal vitamin B-12 levels among ART-Naïve HIV positive individuals in an urban cohort in Uganda
(Public Library of Science, 2012-07-02)
Malnutrition is common among HIV-infected individuals and is often accompanied by low serum levels of micronutrients. Vitamin B-12 deficiency has been associated with various factors including faster HIV disease progression ...