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Assessment of diagnostic capacity of private practitioners in detection of tuberculosis in Juba City, South Sudan
(Makerere University, 2013)
Introduction
Tuberculosis (TB) remains a public health threat globally and is of major health concern in South Sudan. In 2012, TB notification rate for South Sudan was 88/100,000 for new cases and 96/100,000 for all ...
Factors associated with adherence to anti-tuberculosis treatment among children attending TB clinics in Mulago Hospital, Nsambya Home Care and Kawempe (KCCA Health Centre).
(Makerere University, 2014)
Introduction: Tuberculosis (TB) is a major cause of mortality and morbidity with about 8.8 million new TB cases globally in 2010.Uganda like most of Sub-Saharan Africa, has a high burden of TB and this is fuelled by the ...
Bronchoalveolar lavage enzyme-linked immunospot for diagnosis of smear-negative tuberculosis in HIV infected patients
(Public Library of Science, 2012-06-26)
Background: Peripheral blood interferon-gamma release assays (IGRAs) have sub-optimal sensitivity and specificity for diagnosis of active pulmonary tuberculosis (TB). However, assessment of local immune responses has been ...
Rifampicin for continuation phase tuberculosis treatment in Uganda: a cost-effectiveness analysis
(Public Library of Science, 2012-06)
Background: In Uganda, isoniazid plus ethambutol is used for 6 months (6HE) during the continuation treatment phase of new tuberculosis (TB) cases. However, the World Health Organization (WHO) recommends using isoniazid ...
Evaluation of capilia TB assay for rapid identification of mycobacterium tuberculosis complex in BACTEC MGIT 960 and BACTEC 9120 blood cultures
(BioMed Central, 2012)
Background: Capilia TB is a simple immunochromatographic assay based on the detection of MPB64 antigen specifically secreted by the Mycobacterium tuberculosis complex (MTC). Capilia TB was evaluated for rapid identification ...
Incidence and predictors of mortality and the effect of tuberculosis immune reconstitution inflammatory syndrome in a cohort of TB/HIV patients commencing antiretroviral therapy
(Lippincott Wilkins & Williams, 2011)
Background: Tuberculosis-HIV (TB-HIV) coinfection remains an
important cause of mortality in antiretroviral therapy (ART)
programs. In a cohort of TB-HIV–coinfected patients starting
ART, we examined the incidence and ...
Nucleic acid amplification tests for diagnosis of smear-negative TB in a high HIV prevalence setting: a prospective cohort study
(Public Library of Science, 2011-01)
Background: Nucleic acid amplification tests are sensitive for identifying Mycobacterium tuberculosis in populations with positive sputum smears for acid-fast bacilli, but less sensitive in sputum-smear-negative populations. ...
An assessment of Makerere University College of Health Sciences: optimizing health research capacity to meet Uganda’s priorities
(BioMed Central, 2011)
Background: Health research is critical to the institutional mission of the Makerere College of Health Sciences (MakCHS). Optimizing the alignment of health research capacity at MakCHS with the health needs and priorities ...
Non-linear mixed effects modeling of liver function biomarkers in TB-HIV patients co-treated with Rifampicin and Efavirenz based regimens
(2013-11)
Introduction
Survival has improved as a result of improved HIV therapy but liver disease remains a critical problem in HIV patients. HIV disease, ART and Tuberculosis treatments have all been documented to cause liver ...
Chest radiographic findings of pulmonary tuberculosis in severely immunocompromised patients with the human immunodeficiency virus
(The British Institute of Radiology, 2012-06)
Objective: We describe chest radiograph (CXR) findings in a population with a high
prevalence of human immunodeficiency virus (HIV) and tuberculosis (TB) in order to
identify radiological features associated with TB; to ...