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Prevalence and factors associated with utilisation of insecticide treated bednets among pregnant women in Gulu District Internally Displaced Persons’ camps
(Makerere University, 2009-09)
Background. Nearly 500 million people suffer a malaria episode every year and about 90% of all malaria deaths in the world today occur in sub-Sahara Africa. In Uganda, malaria accounts for about 30 - 50% of the outpatient ...
Presumptive treatment with sulphadoxine-pyrimethamine versus weekly chloroquine for malaria prophylaxis in children with sickle cell anaemia in Uganda: a randomized controlled trial
(BioMed Central, 2009-10-24)
Background: Malaria carries high case fatality among children with sickle cell anaemia. In Uganda, chloroquine is used for prophylaxis in these children despite unacceptably high levels of resistance. Intermittent presumptive ...
Artemisinin Combination Therapies for Treatment of Uncomplicated Malaria in Uganda
(Public Library of Science, 2006-05)
Objectives: To compare the efficacy and safety of artemisinin combination therapies for the treatment of uncomplicated falciparum malaria in Uganda. Design: Randomized single-blind controlled trial. Setting: Tororo, Uganda, ...
Costs of setting up and maintaining home based management of fever in Kumi District
(2004)
Introduction Prompt and effective treatment of malaria in the under five year old children is essential in malaria control. Death often results from complications of malaria if treatment is not given within 24 hours. In ...
Access to health care for febrile children in Uganda: symptom recognition, care seeking practices and provider choice
(Karolinska Institutet and Makerere University, 2009)
Background: Febrile illnesses including malaria and pneumonia are leading causes of death among children under five in Uganda. Despite government efforts to increase health care access by offering free services at government ...
Complexity of plasmodium falciparum clinical samples from Uganda during short-term culture.
(University of Chicago Press, 2008-08-22)
We cultured Plasmodium falciparum parasites from 98 Ugandan children with malaria and determined the complexity of infection (COI) on the basis of msp-2 polymorphisms daily for 9 days. The mean COI decreased during culture ...
Antimalarial drug levels in biological samples: methods and applications.
(2008-09)
This thesis deals with the development and validation of analytical methods that are field-adapted and their application in the determination of antimalarial drug levels in biological samples. These methods are suitable ...
Effect of HIV-1 infection on malaria treatment outcome in Uganda patients
(Makerere University Medical School, 2007)
Background: Malaria and HIV-1 infection cause significant morbidity and mortality in sub-Saharan Africa. HIV-1 increases risk for malaria with the risk increasing as immunity declines. The effect of HIV-1 infection on ...
Fixed-dose chloroquine and sulphurdoxine/pyrimethamine treatment of malaria: outcome and pharmacokinetic aspect
(Karolinska University Press, 2007)
Selection of parasites with diminished drug susceptibility by amodiaquine-containing antimalarial regimens in Uganda.
(Oxford University Press, 2009-11-04)
Background. Amodiaquine (AQ) is paired with artesunate (AS) or sulfadoxine-pyrimethamine (SP) in recommended antimalarial regimens. It is unclear how readily AQ resistance will be selected with combination chemotherapy. ...