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Prevalence and factors associated with pulmonary tuberculosis in children admitted with severe pneumonia in Mulago Hospital
(Makerere University, 2012)
Introduction: Tuberculosis is a major cause of morbidity and mortality in children with severe pneumonia. A study done in Uganda by Bakeera et al in 2001 found 2% TB in children with severe pneumonia, while a similar study ...
Diagnostic accuracy of the genexpert system among children with pulmonary tuberculosis at Mulago Hospital
(Makerere University, 2012)
Background:
The GeneXpert system is a rapid mycobacteria tuberculosis diagnostic tool which has shown higher sensitivity and was validated for use in children based on successful data among the adult population. This ...
Assessment of diagnostic capacity of private practitioners in detection of tuberculosis in Juba City, South Sudan
(Makerere University, 2013)
Introduction
Tuberculosis (TB) remains a public health threat globally and is of major health concern in South Sudan. In 2012, TB notification rate for South Sudan was 88/100,000 for new cases and 96/100,000 for all ...
Clinical spectrum, risk factors and outcome of immune reconstitution inflammatory syndrome in patients with tuberculosis-HIV coinfection
(International Medical Press, 2012)
BACKGROUND:
Here, we aimed to determine the clinical spectrum, predictors and outcomes of paradoxical tuberculosis-immune reconstitution inflammatory syndrome (TB-IRIS) in a resource-limited setting.
METHODS:
In a ...
Urban movement and alcohol intake strongly predict defaulting from tuberculosis treatment: an operational study
(Public Library of Science, 2012-05-02)
Background:High levels of defaulting from treatment challenge tuberculosis control in many African cities. We assessed defaulting from tuberculosis treatment in an African urban setting.
Methods: An observational study ...
The role of speciation in positive Lowenstein-Jensen culture isolates from a high tuberculosis burden country
(Public Library of Science, 2011-11)
Objective: To determine the need for routine speciation of positive Lowenstein-Jensen mycobacterial cultures in HIVinfected
patients suspected of having pulmonary tuberculosis at Mulago Hospital in Kampala, Uganda.
Methods: ...
Incremental yield of serial sputum cultures for diagnosis of tuberculosis among HIV infected smear negative pulmonary TB suspects in Kampala, Uganda
(PLoS ONE, 2012-05-22)
Background: Sputum culture is the gold standard for diagnosis of pulmonary tuberculosis (PTB). Although mostly used for research, culture is recommended by the World Health Organization for TB diagnosis among HIV infected ...
Bronchoalveolar lavage enzyme-linked immunospot for diagnosis of smear-negative tuberculosis in HIV infected patients
(Public Library of Science, 2012-06-26)
Background: Peripheral blood interferon-gamma release assays (IGRAs) have sub-optimal sensitivity and specificity for diagnosis of active pulmonary tuberculosis (TB). However, assessment of local immune responses has been ...
Prevalence and factors associated with pulmonary tuberculosis among adults in fishing communities of Lake Victoria, Uganda.
(Makerere University, 2012-06)
Background: Although TB is both a treatable and immunizable disease, it still causes a lot of morbidity and mortality globally, and particularly in the developing world. With a national TB incidence of 330 cases of all ...
Chest radiographic findings of pulmonary tuberculosis in severely immunocompromised patients with the human immunodeficiency virus
(The British Institute of Radiology, 2012-06)
Objective: We describe chest radiograph (CXR) findings in a population with a high
prevalence of human immunodeficiency virus (HIV) and tuberculosis (TB) in order to
identify radiological features associated with TB; to ...