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A novle polymorphism in ABCB1 gene, CYP2B6*6 and sex predict single dose efavirenz population pharmacokinetics in Ugandans
(Wiley-Blackwell, 2009)
AIMS Efavirenz exhibits pharmacokinetic variability causing varied clinical response. The aim was to develop an integrated population pharmacokinetic/pharmacogenetic model and investigate the impact of genetic variations, ...
HIV/AIDS patients display lower relative bioavailability of Efavirenz than healthy subjects
(Adis Data Information BV., 2011)
Background: Pharmacokinetic studies of antiretroviral drugs are often conducted in adult healthy subjects, and the results are extrapolated to HIV/AIDS patients. HIV/AIDS, however, is known to cause morphological and ...
Developing standard methods to monitor adherence to antiretroviral medicines and treatment defaulting in resource-poor settings
(2009)
Adherence to antiretrovirals is critical for longterm effective therapy with first-line medicines.This important study describes how groups from the International Network for the Rational Use of Drugs in East Africa developed ...
A consortium approach to competency‑based undergraduate medical education in Uganda: Process, opportunities and challenges.
(Medknow Publications, 2014)
ABSTRACT
Background: Uganda, like the rest of Africa, is faced with serious health challenges including human immunodeficiency virus infection/
acquired immunodeficiency syndrome (HIV/AIDS), other infectious diseases and ...