Browsing College of Health Sciences (CHS) by Subject "TB"
Now showing items 1-20 of 55
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Adherence to tuberculosis treatment and associated factors among adult HIV/TB co-infected out-patients in the continuous treatment phase in Kampala, Uganda
(Makerere University, 2023)Introduction: Tuberculosis (TB) is one of the major public health problems worldwide, mainly affecting middle and low-income countries which account for over 80% of TB cases and deaths. Treatment acceptance and adherence ... -
Adoption of eHealth for community monitoring of TB/HIV services and its predictors among staff of Non-Government Organizations in Kampala, Uganda
(Makerere University, 2023)Background: The use of electronic data capture and digital health technologies can greatly improve patient healthcare outcomes, through augmenting diagnosis, prescription and treatment, and patient-centered care. The global ... -
Assessing the effect of COVID-19 pandemic on tuberculosis (TB) healthcare service utilization, delivery and coping mechanisms at the TB Unit in Mulago National Referral Hospital, Uganda
(Makerere University, 2023-10)Introduction The coronavirus (COVID-19) pandemic affects health system resilience, one of the areas that could have been affected is Tuberculosis (TB) health care yet TB is still a very important problem which is the ... -
Assessing the role of family support on non adherence to TB treatment by patients in Mulago hospital TB clinic
(Makerere University, 2013-08)Background: Drug resistance among tuberculosis patients in sub-Saharan Africa is increasing mainly due to poor adherence to TB treatment despite various interventions aimed at improving treatment completion. Family support ... -
Assessment of diagnostic capacity of private practitioners in detection of tuberculosis in Juba City, South Sudan
(Makerere University, 2013)Introduction Tuberculosis (TB) remains a public health threat globally and is of major health concern in South Sudan. In 2012, TB notification rate for South Sudan was 88/100,000 for new cases and 96/100,000 for all ... -
An assessment of Makerere University College of Health Sciences: optimizing health research capacity to meet Uganda’s priorities
(BioMed Central, 2011)Background: Health research is critical to the institutional mission of the Makerere College of Health Sciences (MakCHS). Optimizing the alignment of health research capacity at MakCHS with the health needs and priorities ... -
Bronchoalveolar lavage enzyme-linked immunospot for diagnosis of smear-negative tuberculosis in HIV infected patients
(Public Library of Science, 2012-06-26)Background: Peripheral blood interferon-gamma release assays (IGRAs) have sub-optimal sensitivity and specificity for diagnosis of active pulmonary tuberculosis (TB). However, assessment of local immune responses has been ... -
Chest radiographic findings of pulmonary tuberculosis in severely immunocompromised patients with the human immunodeficiency virus
(The British Institute of Radiology, 2012-06)Objective: We describe chest radiograph (CXR) findings in a population with a high prevalence of human immunodeficiency virus (HIV) and tuberculosis (TB) in order to identify radiological features associated with TB; to ... -
The clinical, radiological and laboratory features of tuberculosis in children at Mulago Hospital.
(2002)The incidence of tuberculosis (TB) In Uganda is 150-200/100,000 of the population and an estimated incidence of smear positive adult cases of > 110/100,000 of the population. About a half of the ugandan population was ... -
Comparison of models for analysis of time to loss to follow up and associated risk factors among patients receiving tuberculosis treatment from Mbarara Regional Referral Hospital, Uganda
(Makerere University, 2023)Background: Tuberculosis (TB) remains the top infectious killer worldwide. In Uganda, incidence of TB was reported at 200 per 100,000 people per year. Loss to follow up (LTFU) on TB treatment was 13% in Uganda and 10% in ... -
Compensatory mutations in rpoA, rpoC and rpoD genes among rifampicin-resistant Mycobacterium tuberculosis isolates from Uganda
(Makerere University, 2019-11-11)Background; Mycobacterium tuberculosis can acquire resistance to rifampicin through mutations in the rpoB gene. This is normally accompanied by the fitness cost which however can be mitigated by the acquired secondary ... -
Coping with TB immune reconstitution inflammatory syndrome
(Expert Reviews, 2009)The TB immune reconstitution inflammatory syndrome (IRIS) is a relatively frequent complication in HIV–TB-coinfected patients after they start highly active antiretroviral therapy (HAART). There are two forms of TB IRIS: ... -
Effect of COVID-19 period on tuberculosis treatment success; A mixed methods study among tuberculosis patients at Jinja Regional Referral Hospital
(Makerere University, 2022-01)Introduction: Before the COVID-19 pandemic, over 4000 people were dying from TB every day. TB is still a major public health threat globally, but the TB epidemic may be exacerbated by the COVID-19 pandemic. The lockdown ... -
Effect of vitamin d binding protein gene polymorphisms and vitamin d bioavailability on cathelicidin expression in tuberculosis infection and disease
(Makerere University, 2023-01)Background: The human antimicrobial peptide cathelicidin (LL-37) is involved in host innate immunity by the after activation of Toll-like receptors (TLRs), resulting in direct killing of Mycobacterium tuberculosis (MTB). ... -
Evaluation of capilia TB assay for rapid identification of mycobacterium tuberculosis complex in BACTEC MGIT 960 and BACTEC 9120 blood cultures
(BioMed Central, 2012)Background: Capilia TB is a simple immunochromatographic assay based on the detection of MPB64 antigen specifically secreted by the Mycobacterium tuberculosis complex (MTC). Capilia TB was evaluated for rapid identification ... -
Evaluation of suspected tuberculous pleurisy: clinical and diagnostic findings in HIV-1-positive and HIV-negative adults in Uganda
(International Union Against Tuberculosis and Lung Disease, 2001-04)SETTING: National Tuberculosis Treatment Centre, Mulago Hospital, Kampala, Uganda. OBJECTIVES: To compare clinical and radiographic presentation, and diagnostic methods, in adults with tuberculous pleurisy who are negative ... -
Existing capacity to manage pharmaceuticals and related commodities in East Africa: an assessment with specific reference to antiretroviral therapy
(BioMed Central, 2009)Background: East African countries have in the recent past experienced a tremendous increase in the volume of antiretroviral drugs. Capacity to manage these medicines in the region remains limited. Makerere University, ... -
Facilitators and barriers to tuberculosis case notification among private health facilities in Kampala Capital City
(Makerere University, 2022-08)Introduction: The linkage of Private Health Providers (PHPs) is known to improve Tuberculosis (TB) case finding in the fight against the TB epidemic. In Uganda, 58% of people with TB related symptoms seek care initially ... -
Factors associated with adherence to anti-tuberculosis treatment among children attending TB clinics in Mulago Hospital, Nsambya Home Care and Kawempe (KCCA Health Centre).
(Makerere University, 2014)Introduction: Tuberculosis (TB) is a major cause of mortality and morbidity with about 8.8 million new TB cases globally in 2010.Uganda like most of Sub-Saharan Africa, has a high burden of TB and this is fuelled by the ... -
Factors associated with health seeking behaviour of pulmonary tuberculosis patients at Mulago National Referral Tuberculosis Treatment Centre.
(2002-06)SETTING: The study was carried out at Mulago National Referral Tuberculosis Treatment Centre, Kampala, Uganda, East Africa. OBJECTIVE: The study aimed at assessing factors associated with the health-seeking behavior of ...