Browsing College of Health Sciences (CHS) by Author "Obua, Celestino"
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An assessment of Makerere University College of Health Sciences: optimizing health research capacity to meet Uganda’s priorities
Nankinga, Ziadah; Kutyabami, Paul; Kalyango, Joan; Kibuule, Dan; Groves, Sara; Bollinger, Robert C; Obua, Celestino (BioMed Central, 2011)Background: Health research is critical to the institutional mission of the Makerere College of Health Sciences (MakCHS). Optimizing the alignment of health research capacity at MakCHS with the health needs and priorities ... -
Assessment of the drug storage facilities and quality of generic co-formulation tablets (Stavudine, Lamivudine, Nevirapine) at HIV/AIDS treatment centers in Uganda.
Musoke, David; Waako, Paul John; Obua, Celestino (Medwell Journals, 2008)The study investigated the storage facilities and the quality of co-formulation tablets containing stavudine, lamivudine, and nevirapine at four treatment centres in Uganda. A cross-sectional survey of drug storage conditions ... -
Chewing-stick practices using plants with anti-streptococcal activity in a Ugandan rural community
Odongo, Charles Okot; Musisi, Nathan Lubowa; Waako, Paul; Obua, Celestino (2011)Background: The high dental disease burden in developing countries has created a need to explore and develop cheap and accessible methods of dental disease prevention. Traditional toothbrushes (chewing-sticks) prepared ... -
A consortium approach to competency‑based undergraduate medical education in Uganda: Process, opportunities and challenges.
Kiguli, Sarah; Mubuuke, Roy; Baingana, Rhona; Kijjambu, Stephen; Maling, Samuel; Waako, Paul; Obua, Celestino; Ovuga, Emilio; Kaawa‑Mafigiri, David; Nshaho, Jonathan; Kiguli‑Malwadde, Elsie; Bollinger, Robert; Sewankambo, Nelson (Medknow Publications, 2014)ABSTRACT Background: Uganda, like the rest of Africa, is faced with serious health challenges including human immunodeficiency virus infection/ acquired immunodeficiency syndrome (HIV/AIDS), other infectious diseases and ... -
Developing standard methods to monitor adherence to antiretroviral medicines and treatment defaulting in resource-poor settings
Chalker, John; Andualem, Tenaw; Tadeg, Hailu; Gitau, Lillian; Ntaganira, Joseph; Obua, Celestino; Waako, Paul (2009)Adherence to antiretrovirals is critical for longterm effective therapy with first-line medicines.This important study describes how groups from the International Network for the Rational Use of Drugs in East Africa developed ... -
Existing capacity to manage pharmaceuticals and related commodities in East Africa: an assessment with specific reference to antiretroviral therapy
Waako, Paul J.; Odoi-Adome, Richard; Obua, Celestino; Owino, Erisa; Tumwikirize, Winnie; Ogwal-Okeng, Jasper; Anokbonggo, Willy W.; Matowe, Lloyd; Aupont, Onesky (BioMed Central, 2009)Background: East African countries have in the recent past experienced a tremendous increase in the volume of antiretroviral drugs. Capacity to manage these medicines in the region remains limited. Makerere University, ... -
Factors predicting home storage of medicines in Northern Uganda
Ocan, Moses; Bbosa, Godfrey S.; Waako, Paul; Ogwal-Okeng, Jasper; Obua, Celestino (BioMed Central, 2014)Abstract Background Medicines are kept in households Worldwide for first aid, treatment of chronic or acute disease conditions. This promotes inappropriate use of medicines and hence the associated risks. The study ... -
Fixed-dose chloroquine and sulphurdoxine/pyrimethamine treatment of malaria: outcome and pharmacokinetic aspect
Obua, Celestino (Karolinska University Press, 2007) -
Intermittent use of sulphadoxine-pyrimethamine for malaria prevention: A cross-sectional study of knowledge and practices among Ugandan women attending an urban antenatal clinic.
Odongo, Charles O.; Bisaso, Ronald K.; Byamugisha, Josaphat; Obua, Celestino (Malaria Journal, 2014)Abstract Background: The WHO recommends supervised administration of sulphadoxine-pyrimethamine (SP) as intermittent preventive treatment for malaria (IPTp) during pregnancy. Logistical constraints have however favoured ... -
Patterns and predictors of self-medication in Northern Uganda
Ocan, Moses; Bwanga, Freddie; Bbosa, Godfrey S.; Bagenda, Danstan; Waako, Paul; Ogwal-Okeng, Jasper; Obua, Celestino (PLOS One, 2014)Self-medication with antimicrobial agents is a common form of self-care among patients globally with the prevalence and nature differing from country to country. Here we assessed the prevalence and predictors of antimicrobial ... -
Peer counselors' role in supporting patients' adherence to ART in Ethiopia and Uganda
Gusdal, A. K; Obua, Celestino; Andualem, Tenaw; Wahlström, Rolf; Chalker, John; Fochsen, Grethe; INRUD-IAA project, INRUD-IAA project (Routledge, 2011)Our aim was to explore peer counselors’ work and their role in supporting patients’ adherence to antiretroviral treatment (ART) in resource-limited settings in Ethiopia and Uganda. Qualitative semi-structured interviews ... -
Pharmacokinetics and pharmacodynamics of intravenous artesunate during severe malaria treatment in Ugandan adults
Byakika-Kibwika, Pauline; Lamorde, Mohammed; Mayito, Jonathan; Nabukeera, Lillian; Mayanja-Kizza, Harriet; Katabira, Elly; Hanpithakpong, Warunee; Obua, Celestino; Pakker, Nadine; Lindegardh, Niklas; Tarning, Joel; de Vries, Peter J.; Merry, Concepta (BioMed Central, 2012-04-27)Background: Severe malaria is a medical emergency with high mortality. Prompt achievement of therapeutic concentrations of highly effective anti-malarial drugs reduces the risk of death. The aim of this study was to assess ... -
Steady state bioequivalence of generic and innovator formulations of stavudine, lamivudine, and nevirapine in HIV-infected Ugandan adults
Byakika-Tusiime, Jayne; Chinn, Leslie W.; Oyugi, Jessica H.; Obua, Celestino; Bangsberg, David R.; Kroetz, Deanna L. (Public Library of Science, 2008-12-19)Background: Generic antiretroviral therapy is the mainstay of HIV treatment in resource-limited settings, yet there is little evidence confirming the bioequivalence of generic and brand name formulations. We compared the ... -
Substandard rifampicin based anti-tuberculosis drugs common in Ugandan drug market
Ocan, Moses; Vudriko, Patrick; Ntale, Muhammad; Ogwal-Okeng, Jasper; Obua, Celestino (Journal Of Pharmacy And Pharmacological Research, 2013)Background: Tuberculosis (TB) is an important curable infectious disease in Uganda; its treatment however is facing a challenge of increasing drug resistance. Although Rifampicin containing Fixed-Dose Combination (R-FDC) ... -
Use of artemisia annua L. infusion for malaria prevention: mode of action and benefits in a Ugandan community
Ogwang, Patrick E; Ogwal, Jasper O; Kasasa, Simon; Ejobi, Francis; Kabasa, David; Obua, Celestino (SCIENCEDOMAIN International, 2011)Malaria is major public health problem in Uganda endemic in 95% contributing up to 40% of hospital outpatient attendances. Approaches to controlling the disease include; environmental, entomological and medicinal interventions. ... -
Voices on adherence to ART in Ethiopia and Uganda: a matter of choice or simply not an option
Obua, Celestino; Gusdal, Annelie K.; Annelie, K.; Wahlström, Rolf; Tomson, Göran; Peterson, Stefan; Ekström, Anna Mia; Thorson, Anna; Chalker, John; Fochsen, Grethe (Routledge - Taylor & Francis, 2009)This paper explores HIV patients’ adherence to antiretroviral treatment (ART) in resource-limited contexts in Uganda and Ethiopia, where ART is provided free of charge. Qualitative semi-structured interviews were conducted ...