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Point-of-care lactate testing predicts mortality of severe sepsis in a predominantly HIV type 1–infected patient population in Uganda
(Infectious Diseases Society of America, 2008)
Background: Prediction of mortality may improve management and outcomes of patients with sepsis in resource-limited settings. Therefore, we evaluated the ability of a hand-held portable whole-blood lactate (PWBL) analyzer ...
Is it safe to switch from stavudine to zidovudine after developing symptomatic hyperlactatemia?
(African Health Sciences, 2008-06)
Introduction: In resource limited settings patients on antiretroviral treatment who develop stavudine induced hyperlactatemia are often switched to zidovudine on the basis of published studies that demonstrate that this ...
Immune reconstitution disease of the central nervous system
(Lippincott Williams & Wilkins, 2008)
Purpose of review
The purpose of this review is to examine the literature concerning immune reconstitution
disease associated with the central nervous system infections.
Recent findings
Immune reconstitution disease ...
Outcomes of cryptococcal meningitis in Uganda before and after the availability of highly active antiretroviral therapy
(CID, 2008)
Background. Cryptococcal meningitis (CM) is the proximate cause of death in 20%–30% of persons with acquired immunodeficiency syndrome in Africa. Methods. Two prospective, observational cohorts enrolled human immunodeficiency ...
Sexual risk reduction needs of adolescents living with HIV in a clinical care setting
(Taylor & Francis (Routledge), 2008-04)
As anti-retroviral therapy becomes increasingly available, young people living with HIV need tailored support to adopt healthy sexual behaviors. There has been a gap in the availability of culturally appropriate techniques ...
Tuberculosis-associated immune reconstitution inflammatory syndrome: case definitions for use in resource-limited settings
(Elsevier, 2008-08)
The immune reconstitution inflammatory syndrome (IRIS) has emerged as an important early complication of antiretroviral therapy (ART) in resource-limited settings, especially in patients with tuberculosis. However, there ...
Tuberculosis-associated immune reconstitution inflammatory syndrome: case definitions for use in resource-limited settings
(Elsevier, 2008-08)
The immune reconstitution inflammatory syndrome (IRIS) has emerged as an important early complication of antiretroviral therapy (ART) in resource-limited settings, especially in patients with tuberculosis. However, there ...
Can response of a pruritic papular eruption to antiretroviral therapy be used as a clinical parameter to monitor virological outcome?
(Lippincott Williams & Wilkins, 2008)
Background: A pruritic papular eruption (PPE) is a common skin manifestation observed in 12–46% of persons with HIV infection living in tropical countries. Objective: To determine whether PPE responds to HAART and whether ...
Biomarkers of HIV immune reconstitution inflammatory syndrome
(Future Medicine, 2008)
Dysregulation of the immune system drives HIV pathogenesis. As we develop new ways to treat HIV and AIDS, we encounter new clinical ramifications of our treatment on regulatory components of the Immune system. HIV-associated ...