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Bronchoalveolar lavage enzyme-linked immunospot for diagnosis of smear-negative tuberculosis in HIV infected patients
(Public Library of Science, 2012-06-26)
Background: Peripheral blood interferon-gamma release assays (IGRAs) have sub-optimal sensitivity and specificity for diagnosis of active pulmonary tuberculosis (TB). However, assessment of local immune responses has been ...
Rifampicin for continuation phase tuberculosis treatment in Uganda: a cost-effectiveness analysis
(Public Library of Science, 2012-06)
Background: In Uganda, isoniazid plus ethambutol is used for 6 months (6HE) during the continuation treatment phase of new tuberculosis (TB) cases. However, the World Health Organization (WHO) recommends using isoniazid ...
Nucleic acid amplification tests for diagnosis of smear-negative TB in a high HIV prevalence setting: a prospective cohort study
(Public Library of Science, 2011-01)
Background: Nucleic acid amplification tests are sensitive for identifying Mycobacterium tuberculosis in populations with positive sputum smears for acid-fast bacilli, but less sensitive in sputum-smear-negative populations. ...
Chest radiographic findings of pulmonary tuberculosis in severely immunocompromised patients with the human immunodeficiency virus
(The British Institute of Radiology, 2012-06)
Objective: We describe chest radiograph (CXR) findings in a population with a high
prevalence of human immunodeficiency virus (HIV) and tuberculosis (TB) in order to
identify radiological features associated with TB; to ...