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    • Pharmacokinetics of antiretroviral drug varies with formulation in the target population of children with HIV-1 

      Kasirye, P.; Kendall, L.; Adkison, K. K.; Tumusiime, C.; Ssenyonga, M.; Bakeera-Kitaka, S.; Nahirya-Ntege, P.; Mhute, T.; Kekitiinwa, A.; Snowden, W.; Burger, D. M.; Gibb, D. M.; Walker, A. S. (Clinical Pharmacology & Therapeutics (Nature Publishing Group), 2012-02-21)
      The bioequivalence of formulations is usually evaluated in healthy adult volunteers. In our study in 19 HIV-1-infected Ugandan children (1.8–4 years of age, weight 12 to <15 kg) receiving zidovudine, lamivudine, and abacavir ...