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Sub-optimal CD4 reconstitution despite viral suppression in an urban cohort on Antiretroviral Therapy (ART) in sub-Saharan Africa: Frequency and clinical significance
(BioMed Central, 2008-10)
Background: A proportion of individuals who start antiretroviral therapy (ART) fail to achieve adequate CD4 cell reconstitution despite sustained viral suppression. We determined the frequency and clinical significance of ...
Survival of infants born to HIV-positive mothers, by feeding modality, in Rakai, Uganda
(Public Library of Science, 2008-12-09)
Background: Data comparing survival of formula-fed to breast-fed infants in programmatic settings are limited. We compared mortality and HIV-free of breast and formula-fed infants born to HIV-positive mothers in a program ...
Symtomatic hyperlactatemia associated with nucleoside analogue reverse-transcriptase inhibitor use in HIV-infected patients: a report of 24 cases in a resource limited setting (Uganda).
(University of Chicago Press, 2007-04-19)
We describe 24 Ugandan patients with human immunodeficiency virus infection who developed symptomatic hyperlactatemia associated with the use of nucleoside analogues. All patients were receiving combination therapy that ...
Decreased serum opsonic activity against Streptococcus pneumoniae in Human Immunodeficiency Virus–infected Ugandan adults
(Infectious Diseases Society of America, 2003)
Type-specific immunoglobulin G (IgG) to pneumococcal capsular polysaccharide (CPS) and opsonic activity against Streptococcus pneumoniae were evaluated in serum samples from 36 Ugandan adults with community acquired pneumonia ...
Assessment of the drug storage facilities and quality of generic co-formulation tablets (Stavudine, Lamivudine, Nevirapine) at HIV/AIDS treatment centers in Uganda.
(Medwell Journals, 2008)
The study investigated the storage facilities and the quality of co-formulation tablets containing stavudine, lamivudine, and nevirapine at four treatment centres in Uganda. A cross-sectional survey of drug storage conditions ...
Differences in factors associated with initial growth, CD4, and viral load responses to ART in HIV-Infected children in Kampala, Uganda, and the United Kingdom/Ireland
(Lippincott Williams & Wilkins, 2008-12-01)
Background: Few studies have directly compared response to antiretroviral therapy (ART) between children living in wellresourced and resource-limited settings. In resource-limited settings non-HIV contributors could reduce ...
Total lymphocyte count of 1200 is not a sensitive predictor of CD4 lymphocyte count among patients with HIV disease in Kampala, Uganda
(Makerere University Medical School, 2004-08)
Introduction: Total Lymphocyte Count (TLC) has been found to be an inexpensive and useful marker for staging disease, predicting progression to AIDS and death and monitoring response to ART. However, the correlation between ...
Baseline severe anaemia should not preclude use of zidovudine in antiretroviral-eligible patients in resource-limited settings
(BioMed Central, 2010)
Background: Stavudine is no longer recommended as part of first-line therapy for patients initiating antiretroviral therapy (ART) in Uganda. Most patients are currently initiated on zidovudine-containing regimens, which ...
An assessment of Makerere University College of Health Sciences: optimizing health research capacity to meet Uganda’s priorities
(BioMed Central, 2011)
Background: Health research is critical to the institutional mission of the Makerere College of Health Sciences (MakCHS). Optimizing the alignment of health research capacity at MakCHS with the health needs and priorities ...