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Now showing items 11-20 of 23
Complexity of plasmodium falciparum infections and antimalarial drug efficacy at 7 sites in Uganda.
(University of Chicago Press, 2006-03-13)
Malaria infections in Africa frequently include multiple parasite strains.We examined the relationship between the number of infecting Plasmodium falciparum strains and the responses to 3 different combination therapies ...
Linkage to HIV care and survival following inpatient HIV counseling and testing
(Springer, 2010)
Linkage to HIV care and survival in sub-Saharan Africa is not well documented. In 2004 we conducted a randomized trial among medical inpatients in Mulago Hospital to assess the impact of HIV counseling and testing (HCT) ...
Ethical oversight of multinational collaborative research: lessons from Africa for building capacity and for policy
(The Association of Research Ethics Committees, 2007)
Researchers and others involved in the research enterprise from 12 African countries met with those working in ethics and oversight in the United States as part of an effort to develop research ethics capacity. Drawing on ...
Spatial phylodynamics of HIV-1 epidemic emergence in East Africa.
(2009-09-11)
Design—We sought to investigate the evolutionary and historical reasons for the different epidemiological patterns of HIV-1 in the early epidemic. In order to characterize the demographic history of HIV-1 subtypes A and D ...
Caregivers' experience with major depression concealed by physical illness in patients recruited from Central Ugandan Primary Health Care centers
(Sage Publications, 2008)
In this article, we present caregivers’ grapples with major depression seen among their physically ill patients. A thematic analysis of 29 in-depth caregiver interviews identified four themes: (a) caregivers’ perceptions ...
Total lymphocyte count: not a surrogate marker for risk of death in HIV infected Ugandan children
(Lippincott, Williams & Wilkins, 2008-10-01)
Objectives—To determine the utility of Total Lymphocyte Count (TLC) in predicting the 12 month mortality in HIV infected Ugandan children; to correlate TLC and CD4 cell %. Design—This is a retrospective data analysis of ...
Estimating the healthcare burden of osteomyelitis in Uganda
(Elsevier, 2009-08-25)
Chronic osteomyelitis is a considerable healthcare burden in many developing countries, but this burden is poorly quantified. To estimate the clinical burden of osteomyelitis we systematically sampled the medical records ...
Nutritional status and its determinants in children under five years of age in Rweibaare Parish, Bushenyi District.
(2005)
Under-nutrition and infection are the major causes of morbidity and mortality in the developing world. These two problems are interrelated. Under-nutrition compromises barrier function, allowing easier access by pathogens, ...
Sulfadoxine-pyrimethamine plus chloroquine or amodiaquine for uncomplicated falciparum malaria: a randomized, multisite trial to guide national policy in Uganda
(2005)
The use of combinations of inexpensive drugs for the treatment of malaria in Africa has been proposed as an interim policy while awaiting the widespread availability of more effective regimens. We compared sulfadoxinepyrimethamine ...
The liver in HIV in Africa
(International Medical Press, 2005)
As access to antiretroviral therapy improves across the African continent, liver disease is emerging as an important cause of morbidity and mortality among HIV-infected individuals. Although coinfection with hepatitis B ...