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Translocation of rectal flora and its role in pathogenesis of septicemia in children with severe acute malnutrition
(Makerere University, 2018-12-06)
Introduction: Childhood under-nutrition alters gut mucosal permeability and architecture, causing movement of organisms from GIT into circulation. Most studies carried have detailed bacteremia with malnutrition but none ...
Evaluation of mycobacterium tuberculosis thymidylate kinase as diagnostic biomarker for pulmonary tuberculosis among HIV positive individuals at mjap- iss clinic.
(2018-11-28)
Background Tuberculosis (TB) is the leading cause of morbidity & mortality among HIV positive individuals. Diagnosis of TB in context of HIV co-infection remains challenging. Mycobacterium tuberculosis (M.tb) thymidylate ...
Monocyte activation and dysregulation in treated and untreated hiv-1 infected Ugandans.
(Makerere University, 2018-08-30)
Introduction: Mechanism for increased non-AIDs co morbidities in HIV-1infected individuals on combinatorial antiretroviral therapy (cART) still requires exploration. This is majorly attributed to chronic monocyte activation ...
Nk cell responses among hiv-1 sero negative most at risk individuals in Kampala district.
(Makerere University, 2018-10)
With more than 30 years of the HIV-1 epidemic, development of an effective vaccine has faced several challenges including but not limited to determining the perfect animal model to predict the effectiveness of an HIV-1 ...
In vitro antifungal effect of combined extracts of Euphorbia hirta L. And Carica papaya L.
(2018)
Trichophyton rubrum accounts for up to 69.5 % of all dermatophyte infections worldwide including ringworms (Tinea). High costs of treatment, drug resistance, side effects and increasing incidences of such fungal infections ...
Whole genome assembly and functional significance of nonsynonymous genetic variants of mycobacterium tuberculosis Uganda genotype isolated from Kampala, Uganda.
(Makerere University, 2018-12-06)
Background: Mycobacterium tuberculosis complex (MTC) was initially regarded as a highly homogeneous population; however, recent data suggest the causative agents of tuberculosis are more genetically and functionally diverse ...
EFFECT OF INTENSIVE VERSUS STANDARD ANTHELMINTHIC TREATMENT ON INNATE IMMUNE RESPONSES IN HIGH HELMINTH BURDEN UGANDAN FISHING VILLAGES
(Makerere University, 2018-11-22)
Background: Mass drug administration (MDA) was one of the strategies set by the World Health Organization (2012), to eliminate helminths, reduce helminth-associated morbidity and mortality. Following MDA implementation, a ...
Molecular Diversity of HIV-1 among Long Term Non-progressors attending MJAP-ISS clinic, Mulago
(Makerere University, 2018-11)
Background: To date efforts are still being made to develop an efficacious and safe vaccine to stop the spread of Human Immunodeficiency Virus. Long term non-progressors (LTNPs); who harbour the virus but clinically show ...
Knowledge, attitude and use of direction signs among patients and care givers within Mulago national referral hospital.
(Makerere University, 2018-05-07)
Background
Signage is a way of creating knowledge or awareness of where one is going prior to arrival. Signs are used in various environments such as large facilities, schools, roads etc. Before the existence of language, ...
The microbiome in the blood of HAART-Naive HIV positive patients
(2018-11)
Introduction: Infection with HIV results in the loss of gut mucosal CD4 T cells of the Th17 subtype responsible for maintaining integrity of the mucosa well as antimicrobial immunity. This results in an upset in the balance ...