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Quality of Sulfadoxine-pyrimethamine (SP) tablets sold in drug outlets in Arua District, Uganda
(Makerere University, 2010-09)
Background: Sulfadoxine-pyrimethamine (SP) remain a corner stone in intermittent preventive treatment (IPT) of malaria in pregnancy. Reports of substandard and counterfeit antimalarial drugs in Uganda and neighbouring ...
Asymptomatic Bacteriuria in Diabetic patients attending Mulago Hospital
(Makerere University, 2010-08)
Introduction
There are about 285 million people currently living with Diabetes Mellitus (DM) and the
number is expected to reach 438 million in 2030. Intensive management of DM reduces microvascular complications by about ...
Anti-mycobacterial activity and acute toxicity of Erythrina abyssinica, Cryptolepis sanguinolenta and Solanum incanum
(Makerere University, 2010-10)
Tuberculosis (TB) kills approximately two million people annually. Efforts to treat the disease have been made much more difficult due to development of drug resistant TB strains (MDR and XDR TB) and co-infection with HIV ...
Post-market quality of Rifampicin containing fixed-dose combinations of anti-tuberculosis drugs in Kampala, Uganda
(Makerere University, 2010-08)
Background:
Tuberculosis (TB) is an important curable infectious disease in Uganda; its treatment however is facing a challenge of increasing drug resistance. Although Rifampicin containing Fixed-Dose Combination (R-FDC) ...
NeuroAIDS in Africa
(Informa Healthcare, 2010)
In July 2009, the Center for Mental Health Research on AIDS at the National
Institute of Mental Health organized and supported the meeting “NeuroAIDS
in Africa.” This meeting was held in Cape Town, South Africa, and ...
Genetic variations in ABCB1 and CYP3A5 as well as sex influence quinine disposition among Ugandans
(Lippincott Wilkins & Williams, 2010)
Abstract: Quinine is one of the most effective antimalarial drugs, although its clinical use is limited as a result of its narrow safety margin. Quinine is a substrate of the polymorphic p-glycoprotein and CYP3A4/3A5. This ...
Proceedings of the Uganda Medical Laboratory Technology Association (UMLTA)
(Uganda Medical Laboratory Technology Association (UMLTA), 2010)
THE 28TH UMLTA & 5th FEAMLS SCIENTIFIC CONFERENCE THEME: “STRENGTHENING MEDICAL LABORATORY DELIVERY SYSTEM, -A GATEWAY TO ACHIEVING MILLENIUM DEVELOPMENT GOALS” Date: 18th - 19th November 2010 Venue: Churchill Courts Hotel - Gulu
In silico prediction of efavirenz and rifampicin drug–drug interaction considering weight and CYP2B6 phenotype
(The British Pharmacological Society, 2010)
AIMS
This study aimed to test whether a pharmacokinetic simulation model
could extrapolate nonclinical drug data to predict human efavirenz
exposure after single and continuous dosing as well as the effects of
concomitant ...
The reliability of sickling and solubility tests and peripheral blood film method for sickle cell disease screening at dictrict health centers in Uganda
(Clinics in Mother and Child Health, 2010)
Although sickling and solubility tests and peripheral blood film methods are today available for sickle cell disease screening in Uganda, their reliability and ease of applicability have not been determined. This study was ...
Comparison of methods in the recovery of nucleic acids from archival formalin-fixed paraffin-embedded autopsy tissues
(Elsevier, 2010)
Archival formalin-fixed paraffin-embedded (FFPE) human tissue collections are typically in poor states of storage across the developing world. With advances in biomolecular techniques, these extraordinary and virtually ...