Browsing by Author "Quinn, Thomas C."

Now showing items 1-8 of 8

    • The academic alliance for AIDS care and prevention in Africa 

      Quinn, Thomas C. (The Johns Hopkins University AIDS Service, 2001-11)
      In the continent of Africa, AIDS is the leading cause of death, responsible for over 20% of all fatalities. To date, over 16 million people in Africa have died from AIDS, and approximately 26 million or 70% of the world’s ...

    • Evaluation of Dynabeads and Cytospheres Compared With Flow Cytometry to Enumerate CD41 T Cells in HIV-Infected Ugandans on Antiretroviral Therapy 

      Lutwama, Fred; Serwadda, Ronnie; Mayanja-Kizza, Harriet; Shihab, Hasan M.; Ronald, Allan; Kamya, Moses R.; Thomas, David; Johnson, Elizabeth; Quinn, Thomas C.; Moore, Richard D.; Spacek, Lisa A. (Lippincott Williams & Wilkins., 2008-07-01)
      Background: Laboratory-based monitoring of antiretroviral therapy is essential but adds a significant cost to HIV care. The World Health Organization 2006 guidelines support the use of CD4 lymphocyte count (CD4) to define ...

    • HIV Subtype D Is Associated with Dementia, Compared with Subtype A, in Immunosuppressed Individuals at Risk of Cognitive Impairment in Kampala, Uganda 

      Sacktor, Ned; Nakasujja, Noeline; Skolasky, Richard L.; Rezapour, Mona; Robertson, Kevin; Musisi, Seggane; Katabira, Elly; Ronald, Allan; Clifford, David B.; Laeyendecker, Oliver; Quinn, Thomas C. (Clinical Infectious Diseases, 2009)
      Background. In the United States, clade B is the predominant human immunodeficiency virus (HIV) subtype, whereas in sub-Saharan Africa, clades A, C, and D are the predominant subtypes. HIV subtype may have an impact on ...

    • Laboratory medicine in Africa: a barrier to effective health care 

      Petti, Cathy A; Polage, Christopher R; Quinn, Thomas C.; Ronald, Allan R.; Sande, Merle A. (University of Chicago Press, 2006)
      Providing health care in sub-Saharan Africa is a complex problem. Recent reports call for more resources to assist in the prevention and treatment of infectious diseases that affect this population, but policy makers, ...

    • A new model to monitor the virological efficacy of antiretroviral treatment in resource-poor countries 

      Colebunders, Robert; Laurence, John; Shihab, Hasan M.; Semitala, Fred; Lutwama, Fred; Bakeera-Kitaka, Sabrina; Lynen, Lut; Spacek, Lisa; Reynolds, Steven J.; Quinn, Thomas C.; Viner, Brant; Mayanja-Kizza, Harriet; Kamya, Moses, R. (Elsevier, 2006)
      Monitoring the efficacy of antiretroviral treatment in developing countries is difficult because these countries have few laboratory facilities to test viral load and drug resistance. Those that exist are faced with a ...

    • Resurrecting the triple threat: academic social responsibility in the context of global health research 

      Manabe, Yukari C; Jacob, Shevin T; Thomas, David; Quinn, Thomas C.; Ronald, Allan; Coutinho, Alex; Mayanja-Kizza, Harriet; Merry, Concepta (CID, 2009-05-15)
      As a result of the pandemic of human immunodeficiency virus infection, more academic physicians involved in research are working in resource-limited settings, especially in the field of infectious diseases. These researchers ...

    • Spatial phylodynamics of HIV-1 epidemic emergence in East Africa. 

      Serwadda, David; Gray, Rebecca R.; Tatem, Andrew J.; Lamers, Susanna; Hou, Wei; Laeyendecker, Oliver; Sewankambo, Nelson; Gray, Ronald H.; Wawer, Maria J.; Quinn, Thomas C.; Goodenow, Maureen M.; Salemi, Marco (2009-09-11)
      Design—We sought to investigate the evolutionary and historical reasons for the different epidemiological patterns of HIV-1 in the early epidemic. In order to characterize the demographic history of HIV-1 subtypes A and D ...

    • Treatment interruptions predict resistance in HIV-positive individuals purchasing fixed-dose combination antiretroviral therapy in Kampala, Uganda 

      Oyugi, Jessica H.; Byakika-Tusiime, Jayne; Ragland, Kathleen; Laeyendecker, Oliver; Mugerwa, Roy; Kityo, Cissy; Mugyenyi, Peter; Quinn, Thomas C.; Bangsberg, David R. (Lippincott, Williams & Wilkins, 2007)
      Objective: To evaluate adherence, treatment interruptions, and outcomes in patients purchasing antiretroviral fixed-dose combination (FDC) therapy. Design: Ninety-seven participants were recruited into a prospective 24-week ...